{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T09:26:15Z","timestamp":1789032375010,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T00:00:00Z","timestamp":1679356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Lymphomatoid papulosis (LyP) with <jats:italic>DUSP22\u2013IRF4<\/jats:italic> rearrangement is a rare, recently described variant of LyP histopathologically characterized by a biphasic growth pattern, with epidermotropic small\u2010to\u2010medium\u2010sized atypical T\u2010cells and dermal large and transformed T\u2010cells diffusely expressing CD30. LyP with <jats:italic>DUSP22\u2013IRF4<\/jats:italic> rearrangement can mimic other cutaneous lymphoproliferative disorders, particularly primary cutaneous anaplastic large cell lymphoma (PCALCL) or transformed mycosis fungoides (MF). Unlike PCALCL or transformed MF, LyP with <jats:italic>DUSP22\u2013IRF4<\/jats:italic> rearrangement shows an indolent clinical behavior, with frequent spontaneous regression of untreated lesions. Thus, it is important to recognize this rare variant of LyP to avoid misclassification, which may potentially lead to unnecessarily aggressive patient management. To our knowledge, only 13 cases of LyP with <jats:italic>DUSP22\u2013IRF4<\/jats:italic> rearrangement have been reported to date in the English literature. Herein, we describe an additional case of LyP with <jats:italic>DUSP22\u2013IRF4<\/jats:italic> rearrangement in a 63\u2010year\u2010old man and provide a comprehensive literature review with regards to the clinical, histopathologic, and molecular features of this novel entity.<\/jats:p>","DOI":"10.1111\/cup.14426","type":"journal-article","created":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T03:14:57Z","timestamp":1679454897000},"page":"711-716","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Lymphomatoid papulosis with <i>DUSP22\u2013IRF4<\/i> rearrangement: A case report and literature review"],"prefix":"10.1111","volume":"50","author":[{"given":"Na","family":"Niu","sequence":"first","affiliation":[{"name":"Department of Pathology Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan 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