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The typical rash of NLE most closely resembles the rash of subacute cutaneous lupus erythematosus both clinically and histopathologically. We present a case of reactive granulomatous dermatitis (RGD) associated with NLE in a 3\u2010month\u2010old male in whom the initial histopathology and immunohistochemistry were concerning for hematologic malignancy. RGD is a unifying term used to describe cutaneous granulomatous eruptions that occur in response to a variety of stimuli, including autoimmune connective tissue diseases. Our case demonstrates the range of histopathological findings that may be present in the setting of NLE.<\/jats:p>","DOI":"10.1111\/cup.14479","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T01:25:07Z","timestamp":1686705907000},"page":"793-797","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A case of reactive granulomatous dermatitis associated with neonatal lupus erythematosus"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2094-475X","authenticated-orcid":false,"given":"Monica H.","family":"Xing","sequence":"first","affiliation":[{"name":"University of Chicago Pritzker School of Medicine  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7602-2308","authenticated-orcid":false,"given":"Oluwakemi","family":"Onajin","sequence":"additional","affiliation":[{"name":"Section 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