{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T18:32:57Z","timestamp":1789237977544,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,7,2]],"date-time":"2023-07-02T00:00:00Z","timestamp":1688256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mucoepidermoid carcinoma is a malignant neoplasm of exocrine glands that arises predominantly in salivary glands. It is seldom encountered as a primary cutaneous neoplasm, and in those patients, it often involves the external auditory canal. Given their rarity, they can pose a diagnostic challenge and prompt extensive workup. In salivary glands, mucoepidermoid carcinomas commonly harbor <jats:italic>CRTC1<\/jats:italic>\/3<jats:italic>::MAML2<\/jats:italic> fusions; however, genetic alterations of primary cutaneous neoplasms are less characterized, with previous studies reporting <jats:italic>CRTC1<\/jats:italic> rearrangements in the absence of <jats:italic>MAML2<\/jats:italic> aberrations. Herein, we report a case of a primary cutaneous mucoepidermoid carcinoma of the external auditory canal with a <jats:italic>CRTC1::MAML2<\/jats:italic> rearrangement. We also review the clinical, morphologic, and molecular features of this neoplasm and compare them to those reported in the literature and to histopathologic mimics.<\/jats:p>","DOI":"10.1111\/cup.14491","type":"journal-article","created":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T05:45:45Z","timestamp":1688363145000},"page":"947-950","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Primary mucoepidermoid carcinoma of the external auditory canal with a <i>CRTC1::MAML2<\/i> fusion: A case report and a review of literature"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4134-5377","authenticated-orcid":false,"given":"Carlo","family":"De la Sancha","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Indiana University School of Medicine  Indianapolis Indiana 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