{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:21:51Z","timestamp":1785536511517,"version":"3.56.0"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T00:00:00Z","timestamp":1693872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ointment pseudo\u2010cheilitis is a recently recognized distinctive type of self\u2010induced cheilitis. Lesions consist of a variable amount of crusts adhered to the vermilion. These crusts consist of dried saliva and dead cells mixed with applied medications attached to the lip surface. Patients are typically severely anxious or depressed; the condition impacts quality of life. Ointment pseudo\u2010cheilitis is frequently misdiagnosed as exfoliative cheilitis or cheilitis glandularis. Biopsy reports are often non\u2010revealing because there are no established histopathological criteria for this disease, and clinicians usually do not formulate the correct diagnostic hypothesis. Here, we present the histopathological findings of four cases of ointment pseudo\u2010cheilitis. The most consistent finding was the presence of laminated parakeratotic material detached from the epithelium in biopsies that are devoid of other significant diagnostic changes. This material at the lip surface possibly represents physiologic labial desquamation mixed with dried saliva and applied medication. With this report, we intend to alert dermatopathologists to the diagnosis of ointment pseudo\u2010cheilitis if they receive biopsies from patients who present clinically exuberant labial lesions that show only minimal histopathological changes.<\/jats:p>","DOI":"10.1111\/cup.14534","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T01:20:30Z","timestamp":1693963230000},"page":"53-57","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Histopathologic findings in ointment pseudo\u2010cheilitis: An alert to dermatopathologists"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7968-0624","authenticated-orcid":false,"given":"Marcello Menta Simonsen","family":"Nico","sequence":"first","affiliation":[{"name":"Department of Dermatology, Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Ollague Sierra","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital General Guasmo Sur  Guayaquil Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Gon\u00e7alves","family":"Moya","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Vanessa","family":"Louren\u00e7o","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dental School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1203475418825112"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2021.09.012"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2019.31.3.361"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13142"},{"key":"e_1_2_6_6_1","article-title":"Cheilitis glandularis of both lips: successful treatment with a combination of an intralesional steroid injection and tacrolimus ointment","volume":"2018","author":"Sugaya N","year":"2018","journal-title":"Case Rep Dent"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0557"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2012.24.4.455"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.06.038"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12059"},{"issue":"6","key":"e_1_2_6_11_1","first-page":"688","article-title":"Contact allergy in chronic eczematous lip dermatitis","volume":"18","author":"Schena D","year":"2008","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199106000-00009"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14534","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T08:29:36Z","timestamp":1703579376000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,5]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/cup.14534"],"URL":"https:\/\/doi.org\/10.1111\/cup.14534","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,5]]},"assertion":[{"value":"2023-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}