{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T20:52:01Z","timestamp":1787950321332,"version":"build-2784847793"},"reference-count":12,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>As dermatopathologists, we routinely diagnose melanocytic nevi, melanomas, and occasionally melanocytomas in our daily clinical practice. However, it is now clearly established that the presence of melanocytic differentiation in a tumor does not necessarily indicate any of the aforementioned diagnoses. Tumors such as clear cell sarcoma, malignant melanotic nerve sheath tumor, PEComa, melanotic neuroectodermic tumor of infancy, and even certain translocation\u2010associated renal cell carcinomas all share the common characteristic of melanin synthesis. Over the past two decades, with the advent of molecular diagnostics, there has been an explosion of new data and discoveries in this field. Examples such as <jats:italic>CRTC1::TRIM11<\/jats:italic> cutaneous tumors and MITF pathway\u2010activated melanocytic tumors (<jats:italic>ACTIN::MITF<\/jats:italic> and <jats:italic>MITF::CREM<\/jats:italic>) have been incorporated into the latest edition of the WHO classification of skin tumors (5th ed). In a recent issue, Alexandrescu et al. reported another case of a dermal\/subcutaneous melanocytic tumor harboring a <jats:italic>MITF::CREM1<\/jats:italic> translocation. In a separate paper within the current issue, Li et al. present a case of clear cell sarcoma with the rare <jats:italic>EWSR1::CREM<\/jats:italic> fusion, which had initially been misdiagnosed as melanoma with regional and distant metastases. We warmly welcome these two very interesting and high\u2010quality articles to our journal, and we eagerly anticipate what the future holds for this fascinating category of tumors.<\/jats:p>","DOI":"10.1111\/cup.14543","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:34:15Z","timestamp":1697502855000},"page":"1116-1118","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["One step at a time: Melanocytic differentiation in fusion\u2010driven cutaneous neoplasms"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9462-652X","authenticated-orcid":false,"given":"Konstantinos","family":"Linos","sequence":"first","affiliation":[{"name":"Department of Pathology &amp; Laboratory Medicine Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196509)18:9<1163::AID-CNCR2820180916>3.0.CO;2-0"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.10.108"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-022-01023-9"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000996"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001952"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001630"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-021-03027-3"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14427"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14390"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13812"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-03-0809"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200412000-00005"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14543","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T09:30:26Z","timestamp":1699522226000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,16]]},"references-count":12,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1111\/cup.14543"],"URL":"https:\/\/doi.org\/10.1111\/cup.14543","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,16]]},"assertion":[{"value":"2023-05-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}