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When present, PT\u2010CTCLs are typically EBV\u2212 and exhibit features of mycosis fungoides\/S\u00e9zary syndrome or CD30+ lymphoproliferative disorders. We present a case of a 75\u2010year\u2010old individual who developed skin lesions 30\u2009years after liver transplantation. Pathologic evaluation of the skin biopsy revealed involvement by a clonal, EBV+ T\u2010cell population of gamma\/delta lineage with no evidence of systemic disease. Comprehensive genomic profiling was performed, confirming focal one\u2010copy loss of 6q23.3, altogether consistent with the extremely rare and unusual diagnosis of primary cutaneous EBV+ extranodal NK\/T\u2010cell lymphoma of gamma\/delta T\u2010cell lineage in the posttransplantation setting.<\/jats:p>","DOI":"10.1111\/cup.14677","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T01:41:00Z","timestamp":1720662060000},"page":"777-782","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Primary cutaneous <scp>EBV<\/scp>+ extranodal <scp>NK<\/scp>\/T\u2010cell lymphoma of gamma\/delta T\u2010cell lineage in the posttransplantation setting"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6696-7909","authenticated-orcid":false,"given":"Jessica F.","family":"Williams","sequence":"first","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabienne M.","family":"Lucas","sequence":"additional","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben D.","family":"Carrasco","sequence":"additional","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott B.","family":"Lovitch","sequence":"additional","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Dana\u2010Farber Cancer Institute, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas S.","family":"Kupper","sequence":"additional","affiliation":[{"name":"Department of Dermatology Dana\u2010Farber Cancer Institute, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Sadigh","sequence":"additional","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1702693"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003568"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.10.015"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/00313020701329831"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e318164cf6e"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.60"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12281"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14214"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.16300"},{"key":"e_1_2_8_11_1","volume-title":"Haematolymphoid Tumours; 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