{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T19:39:46Z","timestamp":1771357186209,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mesenchymal tumors may display morphologic and immunohistochemical overlap with melanocytic tumors, presenting a pitfall for misdiagnosis. We report a 62\u2010year\u2010old woman who presented with a recurrent dermal and subcutaneous tumor over the Achilles tendon 15\u2009years following complete excision. Both the primary and the recurrent tumors were characterized by nests and sheets of epithelioid and spindle cells with eosinophilic cytoplasm and uniform ovoid nuclei. The tumor was positive for S100, SOX10, HMB45, cathepsin K, and p63 (weak), while negative for Melan\u2010A, MiTF, smooth muscle actin, and desmin. Gene fusion analysis of the recurrent tumor revealed a <jats:italic>NONO::TFE3<\/jats:italic> fusion which has been recently reported in two similar cutaneous cases. Our case highlights the potential of a <jats:italic>NONO::TFE3<\/jats:italic> cutaneous epithelioid and spindle cell tumor to recur after a prolonged disease\u2010free interval without evidence of high\u2010grade transformation or distant metastasis. Our findings support its classification as a cutaneous mesenchymal neoplasm of intermediate malignancy.<\/jats:p>","DOI":"10.1111\/cup.14712","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T09:54:35Z","timestamp":1724925275000},"page":"954-958","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A case of <i>NONO::TFE3<\/i> cutaneous epithelioid and spindle cell tumor with local recurrence after complete excision"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1114-817X","authenticated-orcid":false,"given":"Joseph S.","family":"Durgin","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily H.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Dermatology Saint Louis University School 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