{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T05:22:32Z","timestamp":1739337752872,"version":"3.37.0"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A 67\u2010year\u2010old male presented with plaques around the orbit and ecchymosis on the neck and back of hands for 2\u2009years. Physical examination showed seborrheic\u2010keratosis\u2010like plaques around the orbit, ecchymosis on the neck and back of hands, as well as nail dystrophy. Serum \u03bb light chain was positive. Histopathological examination demonstrated multiple keratinous cysts in the dermis and eosinophilic homogeneous material in the dermis, which was positive for Congo red with apple\u2010green birefringence on polarized light. Kidney biopsy showed deposition of acellular eosinophilic material in the arteriole wall. Congo red staining was positive. A bone marrow biopsy revealed multiple myeloma. The diagnosis of primary systemic amyloidosis with multiple myeloma was made.<\/jats:p>","DOI":"10.1111\/cup.14763","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T11:11:54Z","timestamp":1734693114000},"page":"194-198","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary Systemic Amyloidosis Characterized by Multiple Keratinous Cysts: A Case Report"],"prefix":"10.1111","volume":"52","author":[{"given":"Xiaoou","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Dermatology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwei","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Pathology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demin","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Nephrology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengjuan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiali","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Dermatology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongquan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019\u20105154.177767"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.5114\/ceji.2014.42126"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102020\u2010239478"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20104362.2002.01411.x"},{"issue":"2","key":"e_1_2_9_6_1","first-page":"E10","article-title":"Nontender Nodules on the Lower Lip. The Diagnosis: Primary Systemic Amyloidosis","volume":"94","author":"Smith J. R.","year":"2014","journal-title":"Cutis"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijt.ijt_6_18"},{"key":"e_1_2_9_8_1","first-page":"1570","volume-title":"China Clinical Dermatology","author":"Bian Z.","year":"2017"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2006.00046"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.4084\/MJHID.2013.005"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13000\u2010015\u20100407\u20109"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00795\u2010004\u20100285\u20109"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/idoj.IDOJ_175_18"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.1103a23"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14763","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T10:00:15Z","timestamp":1739268015000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,20]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1111\/cup.14763"],"URL":"https:\/\/doi.org\/10.1111\/cup.14763","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"type":"print","value":"0303-6987"},{"type":"electronic","value":"1600-0560"}],"subject":[],"published":{"date-parts":[[2024,12,20]]},"assertion":[{"value":"2024-02-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}