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We present a case of a patient with hidradenitis suppurativa and porokeratosis, two AIKDs, followed by a review of these conditions as well as other AIKDs. This case was distinguished by hypertrophic porokeratoses involving cystic hair follicles, showing histopathologic features of both conditions within single biopsy specimens. The patient's course was additionally complicated by SCC arising within a porokeratosis. Our case demonstrates a rare overlap of two AIKDs, occurring not only within the same patient but also within the same lesions.<\/jats:p>","DOI":"10.1111\/cup.14774","type":"journal-article","created":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T12:34:28Z","timestamp":1735907668000},"page":"272-277","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Patient With Concurrent Hidradenitis Suppurativa and Porokeratosis Palmaris et Plantaris Disseminata: Case Report and Review of Autoinflammatory Keratinization Diseases"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1798-6294","authenticated-orcid":false,"given":"Meredith C.","family":"Rogers","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Texas Southwestern Medical Center  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5164-1471","authenticated-orcid":false,"given":"Mark","family":"Ash","sequence":"additional","affiliation":[{"name":"Empire Dermatology  Syracuse New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4682-0154","authenticated-orcid":false,"given":"Amanda","family":"Hernandez","sequence":"additional","affiliation":[{"name":"ProPath  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6281-0565","authenticated-orcid":false,"given":"Gregory A.","family":"Hosler","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Texas Southwestern Medical Center  Dallas Texas USA"},{"name":"ProPath  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.05.019"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00280"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.01.010"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00847"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-014-0097-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2014.3456"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2012.05472.x"},{"issue":"11","key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1111\/j.1610-0387.2012.07976.x","article-title":"Combination of Adalimumab With Traditional Systemic Antipsoriatic Drugs\u2014A Report of 39 Cases","volume":"10","author":"Philipp S.","year":"2012","journal-title":"Journal der Deutschen Dermatologischen Gesellschaft"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v28.i47.6743"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1074329"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1751-2980.12867"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2022.07.032"},{"issue":"10","key":"e_1_2_6_14_1","first-page":"2249","article-title":"Dermatologic Disease\u2010Directed Targeted Therapy (D(3)T(2)): The Application of Biomarker\u2010Based Precision Medicine for the Personalized Treatment of Skin Conditions\u2010Precision Dermatology","volume":"12","author":"Cohen P. 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