{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T03:05:27Z","timestamp":1779246327388,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We report a case of a 3\u2010year\u2010old male who presented with fever, posterior cervical lymphadenopathy, and a tender vesiculobullous lesion on the scalp following contact with goats 2 weeks prior. Histopathology revealed epidermal necrosis, massive papillary dermal edema, brisk mixed inflammation with abundant neutrophils, and inclusion bodies in the epidermis. These findings led to a diagnosis of orf virus infection, otherwise known as ecthyma contagiosum, which is a parapox virus acquired from goats and sheep. An abundance of neutrophils is not a feature classically thought to be associated with orf virus. Additionally, orf typically affects the hands following direct contact with infected animals; the scalp is an unusual site of infection. We suspect infection occurred as this child's scalp when standing was roughly the same height as a goat's mouth, and goats have a predilection to chew at hair. Unfortunately, despite extensive attempts, we were unable to find any laboratory that offers molecular testing for orf on formalin\u2010fixed paraffin\u2010embedded tissue samples. Because of the lack of readily available molecular testing for this infection, we seek to highlight the importance of considering orf in the differential diagnosis of vesicular lesions and obtaining animal exposure history to aid in this diagnosis.<\/jats:p>","DOI":"10.1111\/cup.70077","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:02:49Z","timestamp":1773014569000},"page":"502-505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Wrong Place at the Right Height: Scalp Orf in a Toddler With Dense Dermal Neutrophilic Infiltrate Mimicking Sweet Syndrome"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2485-5321","authenticated-orcid":false,"given":"Alexandra","family":"Kiszluk","sequence":"first","affiliation":[{"name":"Stritch School of Medicine Loyola University Chicago  Maywood Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael W.","family":"Woodfin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Geisinger Medical Center  Danville Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7397-2159","authenticated-orcid":false,"given":"Jerad M.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Geisinger Medical Center  Danville Pennsylvania USA"},{"name":"Department of Laboratory Medicine Geisinger Medical Center  Danville Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-019-1999-1"},{"issue":"4","key":"e_1_2_9_3_1","first-page":"280","article-title":"Human Orf: An Under\u2010Recognized Entity","volume":"27","author":"Santiago L.","year":"2019","journal-title":"Acta Dermatovenerologica Croatica"},{"key":"e_1_2_9_4_1","volume-title":"StatPearls","author":"Efridi 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https:\/\/www.cdc.gov\/laboratory\/specimen\u2010submission\/detail.html?CDCTestCode=CDC\u201010515."},{"key":"e_1_2_9_15_1","unstructured":"Washington Animal Disease Diagnostic Laboratory \u201cContagious Ecthyma (Orf) PCR \u201d 2025 https:\/\/tests.waddl.vetmed.wsu.edu\/Tests\/Details\/8196."},{"key":"e_1_2_9_16_1","unstructured":"Texas A&M Veterinary Medical Diagnostic Laboratory \u201cParapoxvirus (rtPCR) \u201d 2025 https:\/\/tvmdl.tamu.edu\/tests\/parapoxvirus\u2010rtpcr."},{"key":"e_1_2_9_17_1","unstructured":"Government of Canada \u201cIsolation of Orf Virus \u201d accessed March 30 2025 https:\/\/cnphi.canada.ca\/gts\/reference\u2010diagnostic\u2010test\/5168?alphaReturn=diseaseByLetter&alphaChar=O&."}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.70077","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.70077","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.70077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T02:05:57Z","timestamp":1779242757000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.70077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,8]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/cup.70077"],"URL":"https:\/\/doi.org\/10.1111\/cup.70077","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,8]]},"assertion":[{"value":"2025-10-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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