{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T11:00:54Z","timestamp":1784890854075,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Cutaneous crystal\u2010storing histiocytosis (CSH) is an extremely rare histopathologic finding of histiocytes accumulating crystals of immunoglobulin or paraproteins, often associated with lymphoplasmacytic malignancies. It commonly presents in a wide age range of both female and male adults with a history of a lymphoproliferative disorder. Dermatologic examination typically shows cutaneous nodules, plaques, or papules, which frequently present on the trunk, proximal extremities, head, and neck. Histopathologic examination demonstrates numerous large eosinophilic CD68\u2010positive histiocytes with a wavy\u2010granular appearance. Ultrastructural examination of the histiocytes shows refractile needle\u2010like or rhomboid crystals in the cytoplasm. The crystals are composed of immunoglobulins, and typically, there is an associated monotypic B\u2010cell population, often lymphoplasmacytic lymphoma or multiple myeloma. Herein, we describe a case with a striking clinical presentation of cutaneous CSH involving the entirety of the face, neck, chest, shoulders, and upper arms of a 63\u2010year\u2010old female with a history of marginal zone lymphoma (MZL).<\/jats:p>","DOI":"10.1111\/cup.70083","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T23:33:48Z","timestamp":1773185628000},"page":"576-580","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cutaneous Crystal\u2010Storing Histiocytosis With Marginal Zone Lymphoma. A Case Report With A Striking Clinical Presentation"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6406-0132","authenticated-orcid":false,"given":"Ashton","family":"Arlen","sequence":"first","affiliation":[{"name":"University of Texas at Tyler School of Medicine  Tyler Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad S.","family":"Graham","sequence":"additional","affiliation":[{"name":"Dermatology\/Dermatopathology US Dermatology Partners  Tyler Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6281-0565","authenticated-orcid":false,"given":"Gregory A.","family":"Hosler","sequence":"additional","affiliation":[{"name":"Dermatopathology Division ProPath\/Sonic Healthcare  Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marsha C.","family":"Kinney","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Texas Health Science Center San Antonio  Tyler Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440\u20101827.1987.tb03142.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13020271"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14625"},{"key":"e_1_2_9_5_1","unstructured":"D.Lynch \u201cCrystal Storing Histiocytosis \u201d2016 PathologyOutlines.com accessed September 21 2025 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