{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T17:55:08Z","timestamp":1785779708163,"version":"3.56.0"},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Cutaneous lupus erythematosus (CLE) is a well\u2010known autoimmune disorder within dermatology. However, findings of lipid\u2010laden macrophages and xanthomas in a subset of these cases are less understood and usually labeled as a rare, incidental finding. For this reason, a very limited amount of literature has been published regarding the phenomenon. We reviewed 84 cases diagnosed as CLE from 2022 to 2024 from our dermatopathology laboratory. Of the 84 cases of CLE, 9 (11%) demonstrated xanthomatous changes, with 67% sub\u2010classified as discoid lupus and 33% as lupus panniculitis. CLE with xanthomatous reactions may be more common than once thought, as our sampling revealed a prevalence of 11%. Further studies are needed to investigate prevalence as well as possible clinical correlations, as these could influence diagnosis, prognosis, and treatment for this subset of cases.<\/jats:p>","DOI":"10.1111\/cup.70110","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T03:57:21Z","timestamp":1777262241000},"page":"819-823","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Xanthomatous Reactions in Cutaneous Lupus Erythematosus\u2014More Than an Incidental Finding?"],"prefix":"10.1111","volume":"53","author":[{"given":"Lauren M.","family":"Larson","sequence":"first","affiliation":[{"name":"Wayne State University School of Medicine\/Detroit Medical Center  Detroit Michigan USA"},{"name":"Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1847-7141","authenticated-orcid":false,"given":"Marissa","family":"Yaldo","sequence":"additional","affiliation":[{"name":"Wayne State University School of Medicine\/Detroit Medical Center  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailey","family":"Olds","sequence":"additional","affiliation":[{"name":"Department of Dermatology Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktor N.","family":"Goncharuk","sequence":"additional","affiliation":[{"name":"Department of Dermatology Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darius","family":"Mehregan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010023\u201000774\u20108"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2014.01.021"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.915828"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-15-1220-9"},{"key":"e_1_2_10_6_1","volume-title":"Rosai and Ackerman's Surgical Pathology","author":"Goldblum J. 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