{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T17:55:07Z","timestamp":1785779707173,"version":"3.56.0"},"reference-count":9,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We present a rare case of cutaneous involvement of monomorphic epitheliotropic intestinal T\u2010cell lymphoma (MEITL). A 68\u2010year\u2010old man first presented with multiple purpuric patches which extended from his axilla to his groin. Biopsies demonstrated a dermal\u2010based infiltrate of predominantly medium\u2010sized atypical CD8+\/CD56+\/TCR\u2010\u03b4\u2010\/EBER\u2010 T\u2010lymphocytes with slight epidermotropism associated with extravasated red cells. A diagnosis of primary cutaneous cytotoxic T\u2010cell lymphoma was rendered after presumably excluding systemic lymphoma by staging PET\/CT scan and bone marrow biopsy. One year later, he developed purpuric patches and ulcerations of the tongue and 3 months after that, jejunal perforation. Both tongue biopsy and small bowel resection revealed a similar infiltrate of epitheliotropic CD8+\/CD56+\/TCR\u2010\u03b4\u2010\/EBER\u2010 cytotoxic T\u2010cells. Supportive histopathologic features and the absence of gluten\u2010sensitive enteropathy eventually led to the diagnosis of MEITL in the jejunal resection. In retrospect, his initial cutaneous and oral lesions were a mucocutaneous manifestation of MEITL as well, and systemic involvement was not detected on conventional staging. Cutaneous involvement in MEITL is exceedingly uncommon, and this case underscores the importance of including MEITL in the differential diagnosis of skin biopsies of mostly dermal\u2010based lymphomas with only slight epidermotropism with a CD8+\/CD56+\/TCR\u03b4\u2010\/EBER\u2010 phenotype. Early endoscopic evaluation may facilitate diagnosis of occult intestinal disease.<\/jats:p>","DOI":"10.1111\/cup.70123","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T11:45:04Z","timestamp":1776771904000},"page":"803-808","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cutaneous Manifestation of Monomorphic Epitheliotropic Intestinal T\u2010Cell Lymphoma: A Clue to A Gastrointestinal Malignancy"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5688-6266","authenticated-orcid":false,"given":"Fan Foon","family":"Cheo","sequence":"first","affiliation":[{"name":"Department of Anatomical Pathology Singapore General Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aashna","family":"Farishta","sequence":"additional","affiliation":[{"name":"Rush Medical College  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Briana M.","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyun Z.","family":"Ai","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology, Department of Medicine University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthik","family":"Ganapathi","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura B.","family":"Pincus","sequence":"additional","affiliation":[{"name":"Department of Pathology and Dermatology University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318222dfcd"},{"key":"e_1_2_10_3_1","volume-title":"WHO Classification of Haematolymphoid Tumours, 5th Edition","author":"International Agency for Research on Cancer","year":"2022"},{"issue":"6","key":"e_1_2_10_4_1","first-page":"806","article-title":"Monomorphic Epitheliotropic Intestinal T\u2010Cell Lymphoma: A Study of Four Cases and Review of Literature","volume":"50","author":"Fei F.","year":"2020","journal-title":"Annals of Clinical and Laboratory Science"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12864"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000001855"},{"key":"e_1_2_10_7_1","volume-title":"Skin Lymphoma: The Illustrated Guide","author":"Cerroni 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Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.70123","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.70123","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.70123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T17:24:11Z","timestamp":1785777851000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.70123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,21]]},"references-count":9,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/cup.70123"],"URL":"https:\/\/doi.org\/10.1111\/cup.70123","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,21]]},"assertion":[{"value":"2025-12-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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