{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:26:20Z","timestamp":1758709580428},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,12,12]],"date-time":"2013-12-12T00:00:00Z","timestamp":1386806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To study the use of fine needle aspiration (<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content>) cytology in neonatal biliary atresia (<jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twelve female and nine male patients (age range, 3\u20137\u00a0months; mean age, 4.5\u00a0months) with a pre\u2010operative diagnosis of BA, who were scheduled for Kasia portoenterostomy and selected for intraoperative <jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content>, were studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cholestasis, bile deposits, bile infarcts, hepatitic rosettes enclosing bile plugs, feathery degeneration of hepatocytes and inflammatory cells were seen in the cytological slides. Bile infarcts, rosette formation and inflammatory cells were mainly noticed in type 3 <jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content>. Bile infarcts and hepatitic rosettes are surrogate findings for the diagnosis of the obstructive type of cholestasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>With the help of imaging studies, <jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> in a multidisciplinary setting can be diagnostic of neonatal BA when cytological features suggest the obstructive nature of cholestasis, but this procedure cannot replace completely liver biopsy for this diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cyt.12122","type":"journal-article","created":{"date-parts":[[2013,12,12]],"date-time":"2013-12-12T09:14:46Z","timestamp":1386839686000},"page":"336-339","source":"Crossref","is-referenced-by-count":1,"title":["A study to demonstrate the use of FNA cytology rather than biopsy in the diagnosis of neonatal biliary atresia"],"prefix":"10.1111","volume":"25","author":[{"given":"M.","family":"Mokhtari","sequence":"first","affiliation":[{"name":"Department of Pathology School of Medicine Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. V.","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pathology School of Medicine Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Salimi","sequence":"additional","affiliation":[{"name":"Department of Surgery Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200307000-00003"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2003.12.014"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cupe.2005.10.005"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1084-2756(03)00065-4"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2223\/JPED.1608","article-title":"Extrahepatic biliary atresia: current concept and future directions","volume":"83","author":"Carvalho ED","year":"2007","journal-title":"J Pediatr"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2011-0623-RA"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-1-28"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-9261.43015"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/145749691110000109"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2002.tb00159.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.20020"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21303"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v5.i2.95"},{"key":"e_1_2_6_15_1","first-page":"184","article-title":"Diagnostic accuracy of percutaneous cytodiagnosis of hepatic masses, by ultrasound guided fine needle aspiration cytology","volume":"16","author":"Asghar F","year":"2010","journal-title":"Ann King Edward Med Univ"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-2-5"},{"key":"e_1_2_6_17_1","first-page":"385","article-title":"Needle biopsy of the liver for the diagnosis of nonneoplastic liver diseases","volume":"29","author":"Perry MD","year":"1985","journal-title":"Acta Cytol"},{"key":"e_1_2_6_18_1","first-page":"2207","article-title":"Liver aspiration cytology","volume":"48","author":"Brits CJ","year":"1974","journal-title":"S Afr Med J"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcyt.12122","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.12122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T01:01:26Z","timestamp":1696294886000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cyt.12122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,12]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1111\/cyt.12122"],"URL":"https:\/\/doi.org\/10.1111\/cyt.12122","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"value":"0956-5507","type":"print"},{"value":"1365-2303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,12]]}}}