{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:37:59Z","timestamp":1793144279525,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,12,23]],"date-time":"2015-12-23T00:00:00Z","timestamp":1450828800000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:p>The third iteration of the Bethesda System terminology manual was recently published. This update included changes in the reporting of benign endometrial cells, and guidance for special adequacy situations and for cases in which low grade squamous intraepithelial lesions are accompanied by some cells suggesting that a high grade lesion might also be present. In addition, the manual was increased in size to include more illustrations with special studies and comparisons to histology, a greatly increased reference list, and a new chapter devoted to the modern practice of risk\u2010based management. The third edition of the Bethesda manual is meant to serve as a primary reference for the practice of gynecologic cytology designed to provide a uniform system of reporting Worldwide for clinical, teaching, and research purposes.<\/jats:p>","DOI":"10.1111\/cyt.12300","type":"journal-article","created":{"date-parts":[[2016,1,5]],"date-time":"2016-01-05T15:50:03Z","timestamp":1452009003000},"page":"339-342","source":"Crossref","is-referenced-by-count":38,"title":["Bethesda 2014: improving on a paradigm shift"],"prefix":"10.1111","volume":"26","author":[{"given":"D. C.","family":"Wilbur","sequence":"first","affiliation":[{"name":"Department of Pathology Massachusetts General Hospital and Harvard Medical School Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Nayar","sequence":"additional","affiliation":[{"name":"Department of Pathology Feinberg School of Medicine Northwestern University and Northwestern Medicine Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,23]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1001\/jama.1989.03430070079034","article-title":"The 1988 Bethesda System for reporting cervical\/vaginal cytologic diagnoses","volume":"262","author":"Workshop NCI","year":"1989","journal-title":"JAMA"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1989.03420050087046"},{"key":"e_1_2_2_4_1","unstructured":"BogdanichW.Lax laboratories: the Pap test misses much cervical cancer through labs\u2019 errors. Wall Street Journal. November 2 1987."},{"key":"e_1_2_2_5_1","volume-title":"Diagnostic Cytology of the Uterine Cervix","author":"Patten SF","year":"1978"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.11.1500"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.16.2120"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.16.2140"},{"key":"e_1_2_2_9_1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/jnci\/93.4.293","article-title":"Comparison of three management strategies for patients with atypical squamous cells of undetermined significance","volume":"93","author":"Solomon D","year":"2001","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP3CD9YKYFJDQL"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.55.9948"},{"key":"e_1_2_2_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000331549"},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60551-5"},{"key":"e_1_2_2_14_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2010-0739-OA"},{"key":"e_1_2_2_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.07.024"},{"key":"e_1_2_2_16_1","unstructured":"FDA approves first human papillomavirus test for primary cervical cancer screening2014.http:\/\/www.fda.gov\/newsevents\/newsroom\/pressannouncements\/ucm394773.htm[Accessed 18 August 2015]."},{"key":"e_1_2_2_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21521"},{"key":"e_1_2_2_18_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP8J4ROAVWOSHQ"},{"key":"e_1_2_2_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-11074-5"},{"key":"e_1_2_2_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e318287d329"},{"key":"e_1_2_2_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-87666-5"},{"key":"e_1_2_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasc.2014.03.004"},{"key":"e_1_2_2_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23092"},{"key":"e_1_2_2_24_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.LGT200570"},{"key":"e_1_2_2_25_1","first-page":"172","volume-title":"Tumours of the Uterine Cervix: WHO Classification of Tumours of Female Reproductive Organs","author":"Stoler M","year":"2014"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcyt.12300","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.12300","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T13:53:03Z","timestamp":1694440383000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cyt.12300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1111\/cyt.12300"],"URL":"https:\/\/doi.org\/10.1111\/cyt.12300","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"value":"0956-5507","type":"print"},{"value":"1365-2303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12]]}}}