{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T15:30:00Z","timestamp":1772465400706,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,17]],"date-time":"2016-11-17T00:00:00Z","timestamp":1479340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Endometrial cytology has been widely used as a screening tool in Japan. Traditionally, a three\u2010tier reporting system, consisting of \u2018negative\u2019, \u2018suspicious\u2019 and \u2018positive\u2019 categories, has been used. However, a more descriptive system, the New Terminology in Endometrial Cytology (<jats:styled-content style=\"fixed-case\">NTEMC<\/jats:styled-content>), which is based on the Bethesda System for uterine cervical cytology, was introduced recently. The objective of this study was to validate the <jats:styled-content style=\"fixed-case\">NTEMC<\/jats:styled-content> criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Endometrial cytology specimens that had been categorised as \u2018suspicious\u2019 were collected in our hospital between 2003 and 2013, and from these, 106 specimens with corresponding histological results, were re\u2010evaluated according to the <jats:styled-content style=\"fixed-case\">NTEMC<\/jats:styled-content> criteria. Diagnostic categories were assigned based on that chosen by the majority of the examining members.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Negative, atypical endometrial cells, of undetermined significance (<jats:styled-content style=\"fixed-case\">ATEC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>), atypical endometrial cells for which atypical endometrial hyperplasia or worse cannot be excluded (<jats:styled-content style=\"fixed-case\">ATEC<\/jats:styled-content>\u2010A), endometrial hyperplasia, atypical endometrial hyperplasia and malignancy were selected as the diagnostic categories for 9 (8.5%), 34 (32.1%), 17 (16%), 34 (32.1%), 5 (4.7%) and 7 (6.6%) specimens, respectively. Corresponding histological categories of benign, endometrial hyperplasia, atypical endometrial hyperplasia and malignancy were established in 28 (82.4%), 1 (2.9%), 2 (5.9%) and 3 (8.8%) <jats:styled-content style=\"fixed-case\">ATEC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> specimens, respectively, and in 6 (35.3%), 3 (17.6%), 2 (11.8%) and 6 (35.3%) <jats:styled-content style=\"fixed-case\">ATEC<\/jats:styled-content>\u2010A specimens, respectively. The histological category distribution differed significantly (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001), and there was a significant correlation between corresponding cytological and histological categories (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">ATEC category of NTEMC<\/jats:styled-content> system works well in a practical setting and resembles the Bethesda reporting system <jats:styled-content style=\"fixed-case\">ASC<\/jats:styled-content> (atypical squamous cells) category for cervical cytology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cyt.12401","type":"journal-article","created":{"date-parts":[[2016,11,17]],"date-time":"2016-11-17T09:18:40Z","timestamp":1479374320000},"page":"131-139","source":"Crossref","is-referenced-by-count":6,"title":["Practical usefulness of atypical endometrial cell categories within the new classification of endometrial cytology when applied to conventional smears"],"prefix":"10.1111","volume":"28","author":[{"given":"S.","family":"Munakata","sequence":"first","affiliation":[{"name":"Department of Pathology Sakai City Medical Center Sakai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sakai City Medical Center Sakai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Takase","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sakai City Medical Center Sakai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Okatake","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sakai City Medical Center Sakai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sakai City Medical Center Sakai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Sakai City Medical Center Sakai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Yanoh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology J. 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