{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T23:30:00Z","timestamp":1748993400769,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,2,22]],"date-time":"2018-02-22T00:00:00Z","timestamp":1519257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Fibreoptic bronchoscopy is used for the diagnosis and treatment of several pulmonary diseases. Conventional smear and Liquid\u2010based cytology (LBC) methods are applied to cytology samples of various bronchoscopic techniques. If the cytology sample is sufficient for evaluation, a cell block (<jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content>) can be prepared from the remaining material. The aim of this study is to identify the diagnostic value of conventional smear, <jats:styled-content style=\"fixed-case\">LBC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content> methods in bronchial cytological specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of 329 samples from 240 patients was made and, of these, 144 patients were found to have neoplasia. A blind review of the specimens was performed and all were reclassified individually. The endoscopic findings of the 144 patients with neoplasia were analysed retrospectively. The cytological diagnoses were then compared with the final diagnosis or the endoscopic findings of patients with neoplasia. The sensitivity was calculated for each method, both separately and together.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>It was determined that <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content> led to a 10.1% increase in the diagnostic sensitivity for bronchial aspiration (<jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content>) specimens, while no significant increase was seen in bronchial brush specimens. In <jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content> specimens of neoplasia patients with normal bronchoscopic findings, while three methods were applied together with an increase in the number of cases diagnosed as malignant cytology, there was no significant increase in bronchial brush specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrated that adding cell block to <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LBC<\/jats:styled-content> seemed to contribute the cytological diagnosis in <jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content> materials significantly. Another advantage of <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content> is the opportunity of applying advanced methods such as immunocytochemical and molecular techniques.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cyt.12512","type":"journal-article","created":{"date-parts":[[2018,2,22]],"date-time":"2018-02-22T10:48:41Z","timestamp":1519296521000},"page":"156-162","source":"Crossref","is-referenced-by-count":7,"title":["The diagnostic value of cell blocks in Liquid\u2010Based Cytology of bronchial aspiration and bronchial brushing materials"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8532-0289","authenticated-orcid":false,"given":"C.","family":"Sadullaho\u011flu","sequence":"first","affiliation":[{"name":"Department of Pathology Antalya Training and Research Hospital Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Yaman","sequence":"additional","affiliation":[{"name":"Department of 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