{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:23:07Z","timestamp":1762867387203,"version":"3.37.3"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:00:00Z","timestamp":1521936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Cytology of giant cell tumour of tendon sheath (<jats:styled-content style=\"fixed-case\">GCTTS<\/jats:styled-content>) is often sufficient to diagnose this lesion and has been previously described in small series. The present study was undertaken to evaluate detailed cytomorphological features and differential diagnostic entities and pitfalls in the diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All the cases of <jats:styled-content style=\"fixed-case\">GCTTS<\/jats:styled-content> reported on <jats:styled-content style=\"fixed-case\">FNAC<\/jats:styled-content> were retrieved from July 2007 to June 2017. The cases were reviewed for various cytomorphological features, which were correlated with follow\u2010up histopathology wherever available.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 72 cases of <jats:styled-content style=\"fixed-case\">GCTTS<\/jats:styled-content> were retrieved, follow\u2010up histopathology was available in 20 cases. The common sites of involvement were fingers and palm followed by wrists, elbow, knee, ankle and shoulder. The characteristic cytomorphology consisted of mononuclear cells, multinucleated giant cells and pigment laden macrophages in variable numbers. There were four discordant cases that were confirmed on histopathology as sarcoidosis, melanoma, fibrous histiocytoma and eumycetoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">GCTTS<\/jats:styled-content> can be confused cytologically with giant cell rich lesions of bone and soft tissue and pigment containing lesions including melanoma. <jats:italic>Ladybird cell<\/jats:italic> is a characteristic feature seen in this lesion. Proper clinicoradiological correlation is essential before offering a diagnosis of <jats:styled-content style=\"fixed-case\">GCTTS<\/jats:styled-content> on cytology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cyt.12533","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T07:48:09Z","timestamp":1521964089000},"page":"288-293","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Giant cell tumour of tendon sheath: A 10\u2010year study from a tertiary care centre"],"prefix":"10.1111","volume":"29","author":[{"given":"R.","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Cytology and Gynecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Bharani","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3385-1955","authenticated-orcid":false,"given":"N.","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Histopathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9297-5400","authenticated-orcid":false,"given":"P.","family":"Dey","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1771-091X","authenticated-orcid":false,"given":"R.","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rajwanshi","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,25]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"1038","volume-title":"Enzinger and Weiss's Soft Tissue Tumours","author":"Weiss SW","year":"2001"},{"key":"e_1_2_7_3_1","first-page":"102","volume-title":"WHO Classification of Tumours of Soft Tissue and Bone","author":"Saint Aubain Somerhausen N","year":"2013"},{"key":"e_1_2_7_4_1","first-page":"638","volume-title":"Soft Tissue Tumours","author":"Enzinger FM","year":"1988"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.22840"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000328500"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200004000-00002"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000457828"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9098(199806)68:2<100::AID-JSO5>3.0.CO;2-A"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23825"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1992.tb00959.x"},{"key":"e_1_2_7_12_1","first-page":"1209","volume-title":"Enzinger and Weiss's Soft Tissue Tumours","author":"Weiss SW","year":"2001"},{"key":"e_1_2_7_13_1","first-page":"23","article-title":"Fine needle aspiration biopsy cytology of myositis ossificans","volume":"7","author":"Wakely PE","year":"1994","journal-title":"Mod Pathol"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-002-0640-y"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507321103"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcyt.12533","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.12533","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T13:06:47Z","timestamp":1695474407000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cyt.12533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,25]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/cyt.12533"],"URL":"https:\/\/doi.org\/10.1111\/cyt.12533","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"type":"print","value":"0956-5507"},{"type":"electronic","value":"1365-2303"}],"subject":[],"published":{"date-parts":[[2018,3,25]]},"assertion":[{"value":"2017-12-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}