{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T20:10:17Z","timestamp":1767211817526,"version":"3.40.5"},"reference-count":71,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T00:00:00Z","timestamp":1579824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Fine needle aspiration (<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content>) is a minimally invasive albeit highly effective modality used to detect solid and cystic pancreatic lesions. This manuscript aims to present our experience in diagnosing metastases to the pancreas and highlight the importance of immunocytochemistry in the diagnostic process. It also aims to provide a brief review of the literature on this topic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively searched our archives for cases of metastatic deposits to the pancreas diagnosed with <jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> over a 5\u2010year period. We also reviewed the literature for such cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We describe seven cases from our archives that metastasised to the pancreas. Three of them (43%) represented metastatic renal cell carcinoma while the rest four comprised deposits from a lung adenocarcinoma, a colon adenocarcinoma, an adrenal leiomyosarcoma, and a small cell carcinoma of the urinary bladder, respectively. History of primary malignancy was available for all seven patients. All diagnoses were confirmed with the use of immunostains. In our literature review, similar to our case series, renal cell carcinoma was the most common metastasis to the pancreas managed with <jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> (around one out of three patients; 35%). Of interest, our <jats:styled-content style=\"fixed-case\">endoscopic ultrasound<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> case of pancreatic metastasis from urinary bladder small cell carcinoma is the first reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As metastases to the pancreas are commonly accompanied by diverse prognostic signatures and management strategies compared to primary pancreatic malignancies, their accurate identification is imperative. Pancreatic <jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> is a diagnostic modality that can confirm or exclude metastasis to the organ, especially when immunocytochemistry is applied.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cyt.12793","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T21:23:09Z","timestamp":1575321789000},"page":"96-105","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Evaluation of metastases to the pancreas with fine needle aspiration: A case series from a single centre with review of the literature"],"prefix":"10.1111","volume":"31","author":[{"given":"Kalliopi J.","family":"Ioakim","sequence":"first","affiliation":[{"name":"School of Medicine European University Cyprus  Nicosia Cyprus"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy I.","family":"Sydney","sequence":"additional","affiliation":[{"name":"School of 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