{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T10:12:33Z","timestamp":1775470353127,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,8,16]],"date-time":"2020-08-16T00:00:00Z","timestamp":1597536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The aim of this study was to perform an audit of oral and maxillofacial specimens submitted for cytological diagnosis to verify the importance of this complementary examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of our institutional cytopathology database was performed over an 18\u2010year period. Clinical information and cytological data were collected. Associations between independent variables and outcomes were assessed using the Pearson \u03c7<jats:sup>2<\/jats:sup> test or Fisher's test, with a 5% significance level. When available, the histological diagnosis was compared with cytological diagnosis to identify the percentage of agreement and the specificity, sensitivity and accuracy of cytology in identifying malignant neoplasms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1082 cases were identified, which included 65 different cytological diagnoses. Exfoliative cytology (EC) was performed in 312 cases (29.1%) and fine needle aspiration cytology (FNAC) in 770 cases (70.9%). EC was mainly employed to diagnose oral infectious diseases (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and FNAC to diagnose neoplasms, cystic, reactive and miscellaneous lesions (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Cell\u2010block was performed in 555 FNAC cases (51.3%). Panoptic, Papanicolaou and haematoxylin\u2010eosin staining were performed in FNAC and periodic acid\u2010Schiff in EC (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). In 211 cases (19.5%), the histological diagnosis was available and the percentage agreement with the cytological diagnosis was 41.2%. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy to identify malignant neoplasms were 84.6%, 100%, 100%, 77.8% and 90.0%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>EC was mainly performed for diagnosis of infectious diseases and FNAC for diagnosis of salivary gland tumours, odontogenic lesions, reactive lesions and cervical metastasis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cyt.12891","type":"journal-article","created":{"date-parts":[[2020,7,18]],"date-time":"2020-07-18T10:56:20Z","timestamp":1595069780000},"page":"555-563","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["An audit of cytopathology in the oral and maxillofacial region: 18\u00a0years of experience"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3265-2671","authenticated-orcid":false,"given":"Maria Eduarda","family":"P\u00e9rez\u2010de\u2010Oliveira","sequence":"first","affiliation":[{"name":"Department of Oral Diagnosis Oral Pathology and Semiology Area Piracicaba Dental School State University of Campinas (UNICAMP) Piracicaba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1447-2135","authenticated-orcid":false,"given":"Vivian","family":"Petersen Wagner","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis Oral Pathology and Semiology Area Piracicaba Dental School State University of Campinas (UNICAMP) Piracicaba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6644-3264","authenticated-orcid":false,"given":"Gleyson Kleber","family":"do Amaral\u2010Silva","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis Oral Pathology and Semiology Area Piracicaba Dental School State University of Campinas (UNICAMP) Piracicaba 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