{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T19:33:32Z","timestamp":1767987212023,"version":"3.49.0"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Prostate cancer (PCa) is a frequent and mortal disease. The aim of this study was to introduce a \u201cdiagnosis and handling of PCa in one day\u201d concept, accelerating the handling of PCa patients by giving diagnostic results within 3\u00a0hours with the help of prostate cytology. Standard histology served as the control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>After multiparametric MRI, prostate biopsies were taken and one was used for imprint cytology on superfrost slides. The cytology samples were stained by p63\/p504s double staining, a standard stain in PCa histology, followed by on\u2010site interpretation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 129 patients, 39.5% had a prior history of PCa and were either under active surveillance or had been treated by focal therapy. The others came with suspicion of PCa. In 80.8% of the cases, the cytology and histology results agreed. In low\u2010grade PCa the detection with cytology was more difficult with 72.4% agreement, whereas for intermediate and high\u2010grade PCa the concordance with histology was 81.8 and 90%, respectively. False positive cases were less than 4.0%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cytology of the prostate is unusual, but our study is the first to show it is feasible and gives immediate results that are satisfactory, especially in more aggressive cases. Immunocytology can be easily integrated into the laboratory. Our technique allows quicker handling of PCa, which can soften the psychological impact on men waiting for the diagnosis of PCa.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cyt.12930","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T02:19:37Z","timestamp":1603765177000},"page":"211-216","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Diagnosis of prostate cancer in one day: The benefits of cytology in tumour detection"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8488-543X","authenticated-orcid":false,"given":"Eva","family":"Comp\u00e9rat","sequence":"first","affiliation":[{"name":"GRC5 predictive onco\u2010urology Sorbonne University  Paris France"},{"name":"Department of Pathology Hopital Tenon Sorbonne University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphaele","family":"Renard\u2010Penna","sequence":"additional","affiliation":[{"name":"GRC5 predictive onco\u2010urology Sorbonne University  Paris France"},{"name":"Department of Radiology Hopital La Piti\u00e9 Salp\u00eatri\u00e8re Sorbonne University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val\u00e9rie","family":"Ondet","sequence":"additional","affiliation":[{"name":"GRC5 predictive onco\u2010urology Sorbonne University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e9raldine","family":"Cancel\u2010Tassin","sequence":"additional","affiliation":[{"name":"GRC5 predictive onco\u2010urology Sorbonne University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Cussenot","sequence":"additional","affiliation":[{"name":"GRC5 predictive onco\u2010urology Sorbonne University  Paris France"},{"name":"Department of Urology Hopital Tenon Sorbonne University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.09.046"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.01.033"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgyn.2015.01.003"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000530"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2016.08.003"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-017-0836-0"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5161"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2018.11.031"},{"issue":"1","key":"e_1_2_8_10_1","first-page":"162","article-title":"Benign Conditions That Mimic Prostate Carcinoma: MR Imaging Features with Histopathologic Correlation","volume":"36","author":"Kitzing YX","year":"2016","journal-title":"Radiogr Rev Publ Radiol Soc N Am Inc"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-013-1466-5"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.12930","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cyt.12930","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.12930","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T10:30:03Z","timestamp":1693650603000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cyt.12930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,22]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/cyt.12930"],"URL":"https:\/\/doi.org\/10.1111\/cyt.12930","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"value":"0956-5507","type":"print"},{"value":"1365-2303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,22]]},"assertion":[{"value":"2020-06-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}