{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:46Z","timestamp":1787014066236,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) is widely utilised by cytopathologists. The American College of Radiology (ACR) has also proposed a thyroid imaging reporting and data system (TIRADS) to classify thyroid nodules and guide their selection for fine needle aspiration (FNA). The current study aimed to analyse the usefulness of TBSRTC in thyroid cytology reporting, to examine its histological correlation with TIRADS, and to compare the management of lesions in each cytological category in our institute to the TBSRTC recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>A retrospective study was performed on all thyroid FNAs from a 2\u2010year period at a tertiary care centre. Histological correlations of TBSRTC and ACR TIRADS were examined for cases with surgical follow\u2010up, and the risk of malignancy in each TBSRTC category, and sensitivity and specificity of FNA and TIRADS, were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 337 thyroid FNAs were examined, with histological follow\u2010up in 99 cases. Risk of malignancy in categories I\u2010VI was 9.5%, 2.3%, 0.0, 8%, 87.5% and 100.0%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of FNA were 60.0%, 99.0%, 85.7%, and 97.5%, respectively, while those values for thyroid ultrasound were 90.3%, 72.2%, 92.9% and 65%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The study substantiates the usefulness of TBSRTC in arriving at a more precise diagnosis. Hurthle cell lesions with atypia were the common cause of misdiagnosis. The combination of TIRADS and TBSRTC aids in better stratification of thyroid nodules and in decision making for management of lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cyt.12967","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T11:40:21Z","timestamp":1613734821000},"page":"472-481","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The combination of ACR\u2010Thyroid Imaging Reporting and Data system and The Bethesda System for Reporting Thyroid Cytopathology in the evaluation of thyroid nodules\u2014An institutional experience"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5044-1339","authenticated-orcid":false,"given":"Shanmugasundaram","family":"Sakthisankari","sequence":"first","affiliation":[{"name":"Department of Pathology PSG Institute of Medical Sciences and Research Coimbatore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreenivasan","family":"Vidhyalakshmi","sequence":"additional","affiliation":[{"name":"Department of Pathology PSG Institute of Medical Sciences and Research Coimbatore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivanandam","family":"Shanthakumari","sequence":"additional","affiliation":[{"name":"Department of Pathology PSG Institute of Medical Sciences and Research Coimbatore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balalakshmoji","family":"Devanand","sequence":"additional","affiliation":[{"name":"Department of Radiology PSG Institute of Medical Sciences and Research Coimbatore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udayasankar","family":"Nagul","sequence":"additional","affiliation":[{"name":"Department of Radiology PSG Institute of Medical Sciences and Research Coimbatore 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