{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:57:32Z","timestamp":1747184252712,"version":"3.40.5"},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T00:00:00Z","timestamp":1633910400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Androgen insensitivity syndrome (AIS) is described as a patient's clinical (phenotypical) presentation as a female with male karyotyping. Classically, patients are normal looking females with complaints of primary amenorrhea. The gonads may be found as extra\u2010genital swellings; rarely, the testes may undergo malignant transformation. Thus, gonadectomy is indicated in these patients on attaining puberty. A rare and interesting case of clinically unsuspected AIS in a young female who presented with primary amenorrhea and inguinal swelling is reported. The initial diagnosis was suggested on fine needle aspiration cytology (FNAC) from the inguinal swelling that showed the presence of Sertoli cells. Further family history revealed two similar siblings; karyotyping and histopathology confirmed the diagnosis of AIS in the patient. This case highlights the importance of FNAC in early diagnosis and a multidisciplinary approach to confirm the diagnosis and help in appropriate management.<\/jats:p>","DOI":"10.1111\/cyt.13064","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T10:43:44Z","timestamp":1633344224000},"page":"249-252","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Androgen insensitivity syndrome: Can cytology help?"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8842-323X","authenticated-orcid":false,"given":"Sakshi","family":"Dahiya","sequence":"first","affiliation":[{"name":"Department of Pathology Maulana Azad Medical College &amp; Associated LNJP Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2062-6628","authenticated-orcid":false,"given":"Meeta","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology Maulana Azad Medical College &amp; Associated LNJP Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0231-441X","authenticated-orcid":false,"given":"Shramana","family":"Mandal","sequence":"additional","affiliation":[{"name":"Department of Pathology Maulana Azad Medical College &amp; Associated LNJP Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyam Lata","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Pathology Maulana Azad Medical College &amp; Associated LNJP Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asmita","family":"Rathore","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynaecology Maulana Azad Medical College &amp; Associated LNJP Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawanindra","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Surgery Maulana Azad Medical College &amp; Associated LNJP Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200009213431205"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.77.4.305"},{"key":"e_1_2_8_4_1","first-page":"168","article-title":"Seminoma arising in androgen insensitivity syndrome (testicular feminization syndrome): a case report","volume":"31","author":"Zorlu F","year":"2001","journal-title":"Turk J Cancer"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60071-3"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.108.005520"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000091592"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-5851.89794"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.13064","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cyt.13064","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.13064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T13:17:59Z","timestamp":1693228679000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cyt.13064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,11]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1111\/cyt.13064"],"URL":"https:\/\/doi.org\/10.1111\/cyt.13064","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"type":"print","value":"0956-5507"},{"type":"electronic","value":"1365-2303"}],"subject":[],"published":{"date-parts":[[2021,10,11]]},"assertion":[{"value":"2021-09-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}