{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:20:19Z","timestamp":1782184819399,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,19]],"date-time":"2022-02-19T00:00:00Z","timestamp":1645228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Extra\u2010nodal (NK\/T) cell lymphoma (NKTCL) of nasal type (ENKL) presents with extranodal involvement and is associated with EBV. They are localized primarily to nasal and upper airway region but can rarely involve skin, testis, intestine, muscle, or present as a disseminated disease.\u00a0We present a case of a 65\u2010year\u2010old male presented with bilateral orbital swelling, right parotid swelling, fever, mediastinal nodes, pleural effusion and hepatomegaly. Cytology of pleural fluid showed monomorphic lymphoid cells with folded nuclei, vesicular chromatin, inconspicuous nucleoli and granular cytoplasm. Few histiocytes showing hemophagocytosis were also noted in a background of inflammatory cells. Flow cytometric immunophenotyping of pleural fluid showed abnormal lymphoid cells which were positive for CD45, CD2 and CD56. Histopathological examination of the right eye swelling showed many atypical lymphoid cells which were positive for CD56 and negative for B and T cell markers. Based on morphological and immunophenotypic features a diagnosis of NKTCL, extra\u2010nasal type was suggested. Patient succumbed to the disease despite aggressive therapy.<\/jats:p>","DOI":"10.1111\/cyt.13095","type":"journal-article","created":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T20:44:03Z","timestamp":1641588243000},"page":"518-521","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Extra\u2010nasal NK\/T\u2010cell lymphoma: A rare case with a rarer presentation"],"prefix":"10.1111","volume":"33","author":[{"given":"Chandan","family":"Kumar","sequence":"first","affiliation":[{"name":"Laboratory Oncology Unit Dr B.R.A.I.R.C.H , All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garima","family":"Jain","sequence":"additional","affiliation":[{"name":"Laboratory Oncology Unit Dr B.R.A.I.R.C.H , All India Institute of Medical Sciences  New Delhi 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