{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:32:13Z","timestamp":1789187533932,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:00:00Z","timestamp":1652140800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The efficacy of rapid on\u2010site evaluation (ROSE) combined with computed tomography\u2010guided transthoracic core needle biopsy (CT\u2010guided TCNB) is rarely investigated. This study aimed to evaluate the diagnostic efficiency and safety of ROSE combined with CT\u2010guided TCNB for suspected lung cancer patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Clinical data from 285 patients who received CT\u2010guided TCNB for suspected lung cancer in Huashan Hospital from 2015 to 2018 were retrospectively analysed. Of these 163 patients underwent CT\u2010guided TCNB combined with ROSE (ROSE group), while the remaining 122 patients underwent without ROSE (non\u2010ROSE group). The smears from TCNB were quickly processed with Diff\u2010Quick staining and analysed by a skilled cytologist on\u2010site. The consistency of ROSE with the final clinicopathological diagnosis and the diagnostic efficiency and safety of ROSE combined with CT\u2010guided TCNB in suspected lung cancer patients were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ROSE was highly concordant with pathological diagnosis (\u03ba\u00a0=\u00a00.791;<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), with an accuracy of 95.7%. Diagnostic accuracy was significantly higher in the ROSE compared with the non\u2010ROSE group (96.3% vs 86.1%;<jats:italic>P<\/jats:italic>\u00a0=\u00a00.002), with overall incidences of complications of 36.8% and 23.8%, respectively. Minor pneumothorax without drainage was slightly greater in the ROSE compared with the non\u2010ROSE group (14.1% vs 6.6%;<jats:italic>P<\/jats:italic>\u00a0=\u00a00.046). However, there was no significant difference in serious complications between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ROSE was highly consistent with the final clinicopathological diagnosis for suspected lung cancer. ROSE further improved the diagnostic efficiency of CT\u2010guided TCNB with no increased incidence of serious complications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cyt.13123","type":"journal-article","created":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T09:02:31Z","timestamp":1648803751000},"page":"439-444","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Diagnostic efficiency and safety of rapid<scp>on\u2010site<\/scp>evaluation combined with<scp>CT\u2010guided<\/scp>transthoracic core needle biopsy in suspected lung cancer patients"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9403-9613","authenticated-orcid":false,"given":"Ruzetuoheti","family":"Yiminniyaze","sequence":"first","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Huashan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiujuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Huashan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Huashan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Baoshan District of Huashan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengwei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Huashan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Huashan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daibing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Huashan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Huashan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Health Statistics Airforce Medical University Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengqing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Huashan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21590"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carj.2015.10.005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11547-013-0360-1"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2478\/v10019-012-0004-4"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/crj.13151"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0000000000000339"},{"key":"e_1_2_11_8_1","first-page":"141","article-title":"On\u2010site evaluation of percutaneous CT\u2010guided fine needle aspiration of pulmonary lesions. 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