{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T11:06:50Z","timestamp":1775473610411,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>There are conflicting results on whether the presence of oncocytes modifies the risk of neoplasm (RON) or malignancy (ROM) for thyroid fine\u2010needle aspirates (FNAs): Atypia of undetermined significance AUS and Follicular Neoplasm, FN, or Oncocytic Neoplasm, ON. To our knowledge, the effect of non\u2010invasive follicular thyroid neoplasm with papillary\u2010like nuclear features (NIFTP) has not yet been studied. We compared RON and ROM between follicular type AUS (AUS\u2010FT) and oncocytic type AUS (AUS\u2010OT) and between FN and ON.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      We retrospectively analysed all thyroid FNAs with the diagnostic category of AUS\u2010other or Neoplasm (2005\u20132015). AUS\u2010FT had predominance of microfollicles and AUS\u2010OT had predominance of oncocytes. Histology follow\u2010up was then reviewed and RON, ROM was then calculated and compared (significant at\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). We repeated the search for 2018 to evaluate for NIFTP effect.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Pre\u2010NIFTP, 859\/5063 cases (17%) were AUS\u2010FT, AUS\u2010OT, FN, and ON. Histology follow\u2010up was available for 297 cases (35%). RON was 83\/183 (45%) for AUS\u2010FT, 35\/76 (46%) for AUS\u2010OT, 15\/25 (60%) for FN and 11\/13 (85%) for ON. Post\u2010NIFTP, RON was 11\/31 (35%) for AUS\u2010FT, 5\/8 (63%) for AUS\u2010OT, 1\/2 (50%) for FN and 4\/5 (80%) for ON. For both periods, RON, ROM of AUS\u2010FT was not significantly different than AUS\u2010OT, and no significant differences were observed comparing FN and ON.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The predominance of oncocytes does not modify the implied RON, ROM for categories of AUS or FN\\ON, even after the adoption of NIFTP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cyt.13424","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T08:09:52Z","timestamp":1721117392000},"page":"733-737","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oncocytic\/H\u00fcrthle cell lesions have the same implied risk of neoplasm\/malignancy as their follicular counterparts"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3751-9514","authenticated-orcid":false,"given":"Diana","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Pathology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Alexandra","family":"Hanna","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andra","family":"Frost","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison","family":"Wrenn","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isam","family":"Eltoum","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasc.2023.05.005"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22375"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12022-022-09707-3"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2019.0190"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21391"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000361073"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-13-0431"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2016.0386"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20440"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20132"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2015.0020"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.701877"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2017.0500"},{"key":"e_1_2_11_15_1","volume-title":"The Bethesda Systemfor Reporting ThyroidCytopathology","year":"2018"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.13424","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cyt.13424","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.13424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T05:17:27Z","timestamp":1773638247000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cyt.13424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,16]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/cyt.13424"],"URL":"https:\/\/doi.org\/10.1111\/cyt.13424","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"value":"0956-5507","type":"print"},{"value":"1365-2303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,16]]},"assertion":[{"value":"2024-03-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}