{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T22:33:03Z","timestamp":1791844383806,"version":"4.3.4"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T00:00:00Z","timestamp":1731715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Pleomorphic adenoma (PA) is the most common salivary gland neoplasm worldwide (50%\u201370%). Most cases of PA are straightforward diagnoses. However, the diagnosis may be challenging due to the morphological diversity of PAs, which in many cases is caused by the predominance of one of the three components or the presence of metaplastic epithelium. We present the case of a 64\u2010year\u2010old male with a history of prostate cancer and right submandibular gland excision 16\u2009years ago with an unknown previous diagnosis and recent regrowth of his mass in the surgical bed. The tumour showed a predominant spindle cell morphology, cytokeratin\u2010positivity, variable expression of myoepithelial markers in the cytology and surgical pathology specimens, and novel inversion of the chromosome 8, and LRP1B, PBRM1 and TCF3 mutations.<\/jats:p>","DOI":"10.1111\/cyt.13459","type":"journal-article","created":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T14:53:48Z","timestamp":1731768828000},"page":"180-186","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Myoepithelial\u2010Rich Pleomorphic Adenoma With Novel PLAG1 Inversion on Chromosome 8, and LRP1B, PBRM1 and TCF3 Mutations"],"prefix":"10.1111","volume":"36","author":[{"given":"Maria F.","family":"Gonzalez","sequence":"first","affiliation":[{"name":"Lewis Katz School of Medicine, Temple University Hospital  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0907-7585","authenticated-orcid":false,"given":"Jianming","family":"Pei","sequence":"additional","affiliation":[{"name":"Fox Chase Cancer Center  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9422-7967","authenticated-orcid":false,"given":"Yuan","family":"Rong","sequence":"additional","affiliation":[{"name":"Lewis Katz School of Medicine, Temple University Hospital  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0476-357X","authenticated-orcid":false,"given":"Anjali","family":"Seth","sequence":"additional","affiliation":[{"name":"Department of Pathology, Genomic Cancer Institute Fox Chase Cancer Center  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,16]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"WHO Classification of Tumours Editorial Board \u201cHead and Neck Tumours \u201dLyon France International Agency for Research on Cancer 2023 accessed June 24 2024 WHO Classification of Tumours Series 5th ed. vol. 9 https:\/\/tumourclassification.iarc.who.int\/chapters\/52."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12932"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2020.07.009"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2016-0259-SA"},{"key":"e_1_2_9_6_1","unstructured":"M. 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