{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T04:06:41Z","timestamp":1779682001354,"version":"3.53.1"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"abstract":"ABSTRACT<\/jats:title>\n \n Oncocytic intraductal carcinoma (IDC) is a rare subtype of salivary IDC characterized by an oncocytic cell proliferation surrounded by a p63\u2010positive myoepithelial rim. We presented a case of oncocytic IDC: a 70s\u2010year\u2010old male with a swelling in the right parotid gland. Fine\u2010needle aspiration cytology revealed complex papillary cell clusters with an abundant granular cytoplasm and a small number of myoepithelial cells. The cytologic features corresponded to the histological features of oncocytic IDC. The oncocytic cells were positive for S\u2010100, mammaglobin, anti\u2010mitochondrial antibody, and BRAF V600E. Sanger sequencing further confirmed\n BRAF<\/jats:italic>\n p.V600E variant. Because a definite preoperative cytological diagnosis of oncocytic IDC is challenging, ancillary tests using cell blocks can aid in the diagnosis.\n <\/jats:p>","DOI":"10.1111\/cyt.70085","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T04:00:31Z","timestamp":1779681631000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oncocytic Intraductal Carcinoma of the Parotid Gland With the\n BRAF<\/i>\n p.\n V600E<\/scp>\n Variant"],"prefix":"10.1111","author":[{"given":"Yukiya","family":"Hirata","sequence":"first","affiliation":[{"name":"Department of Diagnostic Pathology Kobe University Hospital Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Nakaguro","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuko","family":"Tsukamoto","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kobe University Hospital Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoe","family":"Jimbo","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kobe University Hospital Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoo","family":"Itoh","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kobe University Hospital Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"222","volume-title":"WHO Classification of Tumours Editorial Board. WHO Classification of Head and Neck Tumours","author":"Bishop J. A.","year":"2024"},{"key":"e_1_2_8_3_1","first-page":"170","volume-title":"WHO Classification of Head and Neck Tumours","author":"Loening T.","year":"2017"},{"issue":"1","key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.path.2020.09.003","article-title":"Intraductal Carcinomas of the Salivary Gland","volume":"14","author":"Todorovic E.","year":"2021","journal-title":"Surgical Pathology Clinics"},{"issue":"2","key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/his.13517","article-title":"Low\u2010Grade Intraductal Carcinoma of the Salivary Gland With Prominent Oncocytic Change: A Newly Described Variant","volume":"73","author":"Nakaguro M.","year":"2018","journal-title":"Histopathology"},{"issue":"3","key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/his.14296","article-title":"Oncocytic Intraductal Carcinoma of Salivary Glands: A Distinct Variant With TRIM33\u2010RET Fusions and BRAF V600E Mutations","volume":"79","author":"Bishop J. A.","year":"2021","journal-title":"Histopathology"},{"issue":"12","key":"e_1_2_8_7_1","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1002\/cncy.22504","article-title":"Cytomorphologic Features of Intraductal Salivary Gland Carcinoma: A Multi\u2010Institutional Study of 13 FNA Cases With Histologic, Molecular, and Clinical Correlations","volume":"129","author":"Viswanathan K.","year":"2021","journal-title":"Cancer Cytopathology"},{"issue":"2","key":"e_1_2_8_8_1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s00428-025-04066-w","article-title":"Intraductal Carcinoma of the Parotid Gland, Mixed Intercalated Duct and Oncocytic Subtype With Mucinous and Serous Acinar Differentiation: Cytologic and Histologic Features of a Novel Morphology","volume":"488","author":"Rammal R.","year":"2026","journal-title":"Virchows Archiv"},{"issue":"3","key":"e_1_2_8_9_1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/his.13990","article-title":"Histopathological Evaluation of Minor Salivary Gland Papillary\u2010Cystic Tumours: Focus on Genetic Alterations in Sialadenoma Papilliferum and Intraductal Papillary Mucinous Neoplasm","volume":"76","author":"Nakaguro M.","year":"2020","journal-title":"Histopathology"},{"issue":"10","key":"e_1_2_8_10_1","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1002\/cncy.22288","article-title":"Salivary Duct Carcinoma: Updates in Histology, Cytology, Molecular Biology, and Treatment","volume":"128","author":"Nakaguro M.","year":"2020","journal-title":"Cancer Cytopathology"},{"issue":"1","key":"e_1_2_8_11_1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s12105-024-01653-2","article-title":"Pure Apocrine Intraductal Carcinoma of Salivary Glands: Reassessment of Molecular Underpinnings and Behavior","volume":"18","author":"Delfin L.","year":"2024","journal-title":"Head and Neck Pathology"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.70085","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cyt.70085","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.70085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T04:00:34Z","timestamp":1779681634000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cyt.70085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,24]]},"references-count":10,"alternative-id":["10.1111\/cyt.70085"],"URL":"https:\/\/doi.org\/10.1111\/cyt.70085","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"value":"0956-5507","type":"print"},{"value":"1365-2303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,24]]},"assertion":[{"value":"2025-10-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"cyt.70085"}}