{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:50:57Z","timestamp":1791273057319,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Crystalloids in salivary gland cytology are uncommonly recognised findings that may provide important diagnostic clues in differentiating neoplastic from non\u2010neoplastic lesions. Among these, amylase crystalloids are typically associated with benign salivary gland lesions, including inflammatory conditions such as sialadenitis and cystic lesions, as well as benign neoplasms such as Warthin tumour and pleomorphic adenoma. We describe a case of a 59\u2010year\u2010old female presenting with a parotid swelling. Ultrasonography revealed a cystic lesion in the parotid gland. Fine needle aspiration yielded yellowish fluid, and cytology smears revealed numerous nonbirefringent rectangular to rhomboidal crystalloids showing characteristic staining properties, consistent with amylase crystalloids, in a background of mixed inflammatory infiltrate. No epithelial component was identified. A diagnosis of chronic sialadenitis with amylase crystalloids (Milan Category II) was rendered. The lesion resolved post\u2010aspiration with no recurrence on follow\u2010up. Recognition of crystalloid morphology on cytology is essential, as it serves as a useful clue towards benign pathology and supports accurate diagnosis of benign salivary gland lesions.<\/jats:p>","DOI":"10.1111\/cyt.70121","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T08:46:07Z","timestamp":1788425167000},"page":"648-651","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["When Crystalloids Tell the Story: Amylase Crystalloids in Salivary Gland Cytology"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7789-6472","authenticated-orcid":false,"given":"Pallavi","family":"Saraf","sequence":"first","affiliation":[{"name":"Department of Pathology All India Institute of Medical Sciences (AIIMS)  Bathinda India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaibhav","family":"Saini","sequence":"additional","affiliation":[{"name":"Department of ENT All India Institute of Medical Sciences (AIIMS)  Bathinda India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubham","family":"Kabra","sequence":"additional","affiliation":[{"name":"Department of Radiology All India Institute of Medical Sciences (AIIMS)  Bathinda India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5714-218X","authenticated-orcid":false,"given":"Gargi","family":"Kapatia","sequence":"additional","affiliation":[{"name":"Department of Pathology All India Institute of Medical Sciences (AIIMS)  Bathinda India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0125-876X","authenticated-orcid":false,"given":"Manjit Kaur","family":"Rana","sequence":"additional","affiliation":[{"name":"Department of Pathology All India Institute of Medical Sciences (AIIMS)  Bathinda India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20539"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.5146\/tjpath.2010.01013"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00666217"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840090115"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23295"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22395"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000330993"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22588"},{"issue":"8","key":"e_1_2_10_10_1","first-page":"709","article-title":"Tyrosine\u2010Rich Crystalloids in Neoplasms and Tissues of the Head and Neck","volume":"110","author":"Harris B. R.","year":"1986","journal-title":"Archives of Pathology & Laboratory Medicine"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22602"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488969"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.70121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cyt.70121","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cyt.70121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:57:07Z","timestamp":1791269827000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cyt.70121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,3]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1111\/cyt.70121"],"URL":"https:\/\/doi.org\/10.1111\/cyt.70121","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"value":"0956-5507","type":"print"},{"value":"1365-2303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,3]]},"assertion":[{"value":"2026-05-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}