{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T14:10:11Z","timestamp":1779286211311,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T00:00:00Z","timestamp":1361836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction and Aims<\/jats:title><jats:p>The study aims to quantify trends in fentanyl prescribing and fentanyl mortality in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia within the context of concern among health professionals concerning increasing accessibility of fentanyl, and the harms that may arise as a result.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and Methods<\/jats:title><jats:p>This paper presents data on prescribing patterns of fentanyl by 10 year age group adjusted by population rate, detailed analyses of fentanyl\u2010related deaths from the <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ational <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>oronial <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nformation <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ystem and deaths adjusted for prescribing levels within <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fentany prescriptions have increased and are most prevalent among <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralians aged over 80 years. One hundred and thirty\u2010six fentanyl\u2010related deaths were recorded during 2000\u20132011; 54% of decedents had a history of injecting drug use and, among this group, 95% had injected fentanyl at the time of death; 62% of deaths recorded misuse (most notably injection) of fentanyl; 50% recorded a history of drug dependence and 40% a mental health problem; 37% recorded a history of chronic pain; and 36% recorded fentanyl as being prescribed at the time of death. Deaths were primarily among <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralians under 47 years of age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>There have been significant increases in fentanyl prescribing in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia. It is unclear what proportion of this increase represents legitimate treatment of pain. Fentanyl deaths have also increased, although mortality is currently low in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia. A large proportion of the deaths involved the injection of diverted fentanyl, highlighting the need for messages regarding safer injecting practices targeting people who inject drugs, and strategies to minimise the risks of diversion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.12033","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T03:51:48Z","timestamp":1361937108000},"page":"269-275","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Trends in fentanyl prescriptions and fentanyl\u2010related mortality in <scp>A<\/scp>ustralia"],"prefix":"10.1111","volume":"32","author":[{"given":"Amanda","family":"Roxburgh","sequence":"first","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucy","family":"Burns","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf H.","family":"Drummer","sequence":"additional","affiliation":[{"name":"Victorian Institute of Forensic Medicine  Melbourne Australia"},{"name":"Department of Forensic Medicine Monash University  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Pilgrim","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine Monash University  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Farrell","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louisa","family":"Degenhardt","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"},{"name":"Centre for Health Policy Programs and Economics School of Population Health University of Melbourne  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,26]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Harmaceuticals: special forum on fentanyl injection and overdoses","author":"Anex","year":"2012"},{"key":"e_1_2_7_3_1","volume-title":"Prescription Opioid Policy: improving management of chronic non\u2010malignant pain and prevention of problems associated with precription opioid use","author":"The Royal Australasian College of Physicians","year":"2009"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69181-2"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2005.05.009"},{"key":"e_1_2_7_6_1","volume-title":"Drug poisoning deaths in the United States, 1980\u20132008","author":"Warner MCL","year":"2011"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.7.3.213"},{"key":"e_1_2_7_8_1","volume-title":"Fentanyl in Europe: EMCDDA trendspotter study","author":"European Monitoring Centre for Drugs and Drug Addiction","year":"2012"},{"key":"e_1_2_7_9_1","first-page":"547","volume-title":"Goodman and Gilman's the pharmacological basis of therapeutics","author":"Gutstein HB","year":"2006"},{"key":"e_1_2_7_10_1","volume-title":"Narcotic drugs: estimated world requirements for 2012; statistics for 2010","author":"International Narcotics Control Board","year":"2011"},{"key":"e_1_2_7_11_1","unstructured":"National Prescribing Service.Fentanyl patches (Durogesic) for chronic pain. Rational assessment of drugs and research 2006 7 August2012."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c4851"},{"key":"e_1_2_7_13_1","unstructured":"IBM. IBM SPSS Statistics Version 20.0 Chicago IL2011."},{"key":"e_1_2_7_14_1","volume-title":"Australian statistics on medicines 2009","author":"Australian Govermnent Department of Health and Ageing","year":"2011"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja10.11450"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2006.01495.x"},{"key":"e_1_2_7_17_1","volume-title":"Blueprint for the Future.","author":"Drug National","year":"2012"}],"container-title":["Drug and Alcohol Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdar.12033","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dar.12033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T13:21:23Z","timestamp":1697635283000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dar.12033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,26]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1111\/dar.12033"],"URL":"https:\/\/doi.org\/10.1111\/dar.12033","archive":["Portico"],"relation":{},"ISSN":["0959-5236","1465-3362"],"issn-type":[{"value":"0959-5236","type":"print"},{"value":"1465-3362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,26]]},"assertion":[{"value":"2012-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-01-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-02-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}