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This paper aimed to undertake a detailed examination of jurisdictional differences in patterns of opioid use among a cohort of people who regularly tamper with pharmaceutical opioids in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and Methods<\/jats:title><jats:p>Data were drawn from the <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ational <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>pioid <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edications <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>buse <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>eterrence study. The cohort was recruited from <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>outh <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>ales (<jats:styled-content style=\"fixed-case\">NSW<\/jats:styled-content>; <jats:italic>n<\/jats:italic>\u2009<jats:italic>=<\/jats:italic>\u2009303), <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>outh <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia (<jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content>; <jats:italic>n<\/jats:italic>\u2009<jats:italic>=<\/jats:italic>\u2009150) and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>asmania (<jats:styled-content style=\"fixed-case\">TAS<\/jats:styled-content>; <jats:italic>n<\/jats:italic>\u2009<jats:italic>=<\/jats:italic>\u2009153) to participate in face\u2010to\u2010face structured interviews collecting data on use of pharmaceutical opioids, benzodiazepines, other sedative drugs and illicit substances, as well as the harms associated with substance use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">TAS<\/jats:styled-content> participants reported greater use and injection of certain pharmaceutical opioids (particularly morphine and methadone tablets), and limited heroin use, with lower rates of engagement in opioid substitution treatment, compared with <jats:styled-content style=\"fixed-case\">NSW<\/jats:styled-content> participants. <jats:styled-content style=\"fixed-case\">NSW<\/jats:styled-content> participants were more socially disadvantaged and more likely to report risky injecting behaviours and injecting\u2010related injuries and diseases compared with <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TAS<\/jats:styled-content> participants. <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content> participants reported greater rates of pain conditions, greater use of pain\u2010based services, as well as broader use of pharmaceutical opioids in regards to forms and route of administration, compared with <jats:styled-content style=\"fixed-case\">NSW<\/jats:styled-content> participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>Distinct jurisdictional profiles were evident for people who tamper with pharmaceutical opioids, potentially reflecting jurisdictional differences in prescribing regulatory mechanisms and addiction treatment models <jats:italic>[Peacock A, Bruno R, Cama E, Kihas I, Larance B, Lintzeris N, Hordern A, White N, Ali R, Degenhardt L. Jurisdictional differences in opioid use, other licit and illicit drug use, and harms associated with substance use among people who tamper with pharmaceutical opioids.<\/jats:italic> Drug Alcohol Rev<jats:italic> 2015;34:611\u201322]<\/jats:italic><\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.12279","type":"journal-article","created":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T07:58:45Z","timestamp":1434614325000},"page":"611-622","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Jurisdictional differences in opioid use, other licit and illicit drug use, and harms associated with substance use among people who tamper with pharmaceutical opioids"],"prefix":"10.1111","volume":"34","author":[{"given":"Amy","family":"Peacock","sequence":"first","affiliation":[{"name":"School of Medicine University of Tasmania  Hobart Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6673-833X","authenticated-orcid":false,"given":"Raimondo","family":"Bruno","sequence":"additional","affiliation":[{"name":"School of Medicine University of Tasmania  Hobart Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Cama","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Kihas","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Briony","family":"Larance","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Lintzeris","sequence":"additional","affiliation":[{"name":"Sydney Medical School Sydney University  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia","family":"Hordern","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2301-8778","authenticated-orcid":false,"given":"Nancy","family":"White","sequence":"additional","affiliation":[{"name":"University of Adelaide  Adelaide Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Ali","sequence":"additional","affiliation":[{"name":"University of Adelaide  Adelaide Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louisa","family":"Degenhardt","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.12551"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61138-0"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12446"},{"key":"e_1_2_8_5_1","unstructured":"Australian Institute of Health and Welfare.2010 National Drug Strategy Household Survey report. 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