{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:33:12Z","timestamp":1783427592477,"version":"3.54.6"},"reference-count":37,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2017,9,20]],"date-time":"2017-09-20T00:00:00Z","timestamp":1505865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction and Aims<\/jats:title><jats:p>To provide an assessment of outcomes in a cohort of opioid\u2010dependent patients post\u2010detoxification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and Methods<\/jats:title><jats:p>This study employed an observational longitudinal cohort design. Patients who completed detoxification in the three major Drug Dependency Units in Ireland during a 14\u2010month period were included in the study (n\u2009=\u2009143). Patients opting for one of the three pathways post\u2010detoxification (inpatient aftercare, outpatient aftercare or no formal aftercare) were assessed in the final week of detoxification and followed up after 3, 6 and 9\u2009months. The primary outcome was abstinence following detoxification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A Cox (adjusted) model indicated participants who opted for outpatient aftercare treatment lapsed\/relapsed at a rate of 52% higher than the inpatient aftercare group (hazard ratio\u2009=\u20091.52, 95% confidence interval 0.75\u20133.08, P\u2009=\u20090.24). Moreover, time to lapse\/relapse was considerably shorter for the no formal aftercare group (hazard ratio\u2009=\u20097.68, 95% confidence interval 4.30\u201313.73, P\u2009=\u20095.75 \u00d7 10<jats:sup>\u221212<\/jats:sup>). Abstinence rates for outpatient aftercare and inpatient aftercare are about equal after 9 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusion<\/jats:title><jats:p>Patients who opt for aftercare post\u2010detoxification have significantly better outcomes at follow up when compared to no formal aftercare. In addition, patients\u2019 intention to attend aftercare affected their outcomes regardless of eventual treatment path.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.12597","type":"journal-article","created":{"date-parts":[[2017,9,20]],"date-time":"2017-09-20T09:26:34Z","timestamp":1505899594000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A naturalistic longitudinal analysis of post\u2010detoxification outcomes in opioid\u2010dependent patients"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7723-8787","authenticated-orcid":false,"given":"Jo\u2010Hanna","family":"Ivers","sequence":"first","affiliation":[{"name":"Department of Public Health and Primary Care Institute of Population Health, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Zgaga","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care Institute of Population Health, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brion","family":"Sweeney","sequence":"additional","affiliation":[{"name":"Tara Trust  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eamon","family":"Keenan","sequence":"additional","affiliation":[{"name":"National Drug Treatment Centre, Health Service Executive  Dublin Ireland"},{"name":"National Office of Social Inclusion, Health Service Executive  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Darker","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care Institute of Population Health, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bobby P.","family":"Smyth","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care Institute of Population Health, Trinity College Dublin  Dublin Ireland"},{"name":"National Drug Treatment Centre, Health Service Executive  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Barry","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care Institute of Population Health, Trinity College Dublin  Dublin Ireland"},{"name":"National Drug Treatment Centre, Health Service Executive  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1465-3362.2011.00349.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2008.05.004"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.2161-1874.1993.tb00083.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2005.06.009"},{"key":"e_1_2_7_6_1","volume-title":"Heroin use in Australia: its impact on public health and public order","author":"Hall W","year":"1999"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2011.03.009"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/0959523031000154445"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70305-0"},{"key":"e_1_2_7_10_1","first-page":"12","article-title":"Opiate dependents\u2019 experiences of the therapeutic relationship in methadone centers; a qualitative study","volume":"1","author":"Banazadeh N","year":"2009","journal-title":"Addict Health"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7396.959"},{"key":"e_1_2_7_12_1","unstructured":"Des CorriganO GormanA. 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