{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:17:27Z","timestamp":1791998247765,"version":"4.4.0"},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Buprenorphine is a partial opioid agonist commonly used to treat opioid dependence. The pharmacology of buprenorphine increases the risk of a precipitated opioid withdrawal when commencing patients on buprenorphine treatment, particularly when transferring from long acting opioids (e.g. methadone). There is little documented experience regarding the management of precipitated withdrawal. In our case, a patient developed a significant precipitated opioid withdrawal following buprenorphine administration, and was able to be successfully treated in hospital with further buprenorphine. This demonstrates that rapid increases in buprenorphine dose can be used as an effective treatment for buprenorphine\u2010induced precipitated opioid withdrawal. The use of buprenorphine to manage withdrawal then allows the individual to continue on this highly effective treatment.<\/jats:p>","DOI":"10.1111\/dar.13228","type":"journal-article","created":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T02:39:35Z","timestamp":1611283175000},"page":"567-571","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Managing opioid withdrawal precipitated by buprenorphine with buprenorphine"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3609-0592","authenticated-orcid":false,"given":"Bridget","family":"Oakley","sequence":"first","affiliation":[{"name":"Drug and Alcohol Services South East Sydney Local Health District  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7193-9566","authenticated-orcid":false,"given":"Hester","family":"Wilson","sequence":"additional","affiliation":[{"name":"Drug and Alcohol Services South East Sydney Local Health District  Sydney Australia"},{"name":"School of Public Health and Community Medicine UNSW Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Hayes","sequence":"additional","affiliation":[{"name":"Drug and Alcohol Services South East Sydney Local Health District  Sydney Australia"},{"name":"School of Public Health and Community Medicine UNSW Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5229-8257","authenticated-orcid":false,"given":"Nicholas","family":"Lintzeris","sequence":"additional","affiliation":[{"name":"Drug and Alcohol Services South East Sydney Local Health District  Sydney Australia"},{"name":"Division Addiction Medicine University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,21]]},"reference":[{"key":"e_1_2_5_2_1","volume-title":"National Guidelines for Medication\u2010assisted Treatment of Opioid Dependence","author":"Gowing L","year":"2014"},{"key":"e_1_2_5_3_1","volume-title":"Evidence supporting treatment. 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