{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T21:25:54Z","timestamp":1788297954137,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T00:00:00Z","timestamp":1631577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>In early 2020, many services modified their delivery of opioid treatment in response to the COVID\u201019 pandemic, to limit viral spread and maintain treatment continuity. We describe the changes to treatment and preliminary analysis of the association with patients' substance use and well\u2010being.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A pre\u2010post comparison of treatment conditions and patient self\u2010reported outcomes using data extracted from electronic medical records in the 5\u00a0months before (December 2019\u2013April 2020) and after (May 2020\u2013September 2020) changes were implemented in three public treatment services in South Eastern Sydney Local Health District.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data are available for 429\/460 (93%) patients. Few (21, 5%) dropped out of treatment. In the \u2018post\u2019 period there was significantly more use of depot buprenorphine (12\u201324%), access to any take\u2010away doses (TAD; 24\u201369%), access to \u22656 TAD per week (7\u201331%), pharmacy dosing (24\u201352%) and telehealth services. There were significant reductions in average opioid and benzodiazepine use, increases in cannabis use, with limited group changes in social conditions, or quality of life, psychological and physical health. At an individual level, 22% of patients reported increases in their use of either alcohol, opioids, benzodiazepines or stimulants of \u22654\u2009days in the past 4\u2009weeks. Regression analysis indicates increases in substance use were associated with higher levels of supervised dosing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>These preliminary findings suggest that the modified model of care continued to provide safe and effective treatment, during the pandemic. Notably, there was no association between more TAD and significant increases in substance use. Limitations are discussed and further evaluation is needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.13382","type":"journal-article","created":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T17:01:00Z","timestamp":1631638860000},"page":"1009-1019","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Opioid agonist treatment and patient outcomes during the <scp>COVID<\/scp>\u201019 pandemic in south east Sydney, Australia"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5229-8257","authenticated-orcid":false,"given":"Nicholas","family":"Lintzeris","sequence":"first","affiliation":[{"name":"Sydney School of Medicine (Central Clinical School), Faculty of Medicine and Health The University of Sydney  Sydney Australia"},{"name":"Drug and Alcohol Services South Eastern Sydney Local Health District  Sydney Australia"},{"name":"NSW Drug and Alcohol Clinical Research and Improvement 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