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A latent class analysis was conducted by leveraging baseline measures of self\u2010reported use of 15 substances in the past 3\u2009months as well as validated screening measures of hazardous alcohol and cannabis use. Correlates of latent class membership were examined using a three\u2010step categorical latent variable logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four typologies of substance use were identified: (i) methamphetamine use only (43%); (ii) methamphetamine and crack\u2010cocaine use (22%); (iii) party and play use\u2014methamphetamine, gamma\u2010hydroxybutyrate and amyl nitrites (i.e. poppers) with erectile dysfunction drugs (31%); and (iv) high polysubstance use (4%). SMM of colour and those with a history of incarceration were more commonly classified as engaging in methamphetamine and crack\u2010cocaine use compared to party and play use. Men with higher sexual compulsivity scores were more commonly classified as engaging in party and play use and polysubstance use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>There is substantial heterogeneity in polysubstance use patterns among SMM living with HIV who use methamphetamine. This will inform the development of tailored substance use interventions addressing the unique needs of SMM of colour and targeting sexual compulsivity as a prominent comorbidity for some men.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.13405","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T04:04:01Z","timestamp":1637553841000},"page":"338-346","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Tina's <scp>P<\/scp><scp>arTy<\/scp> line: Polysubstance use patterns in sexual minority men living with HIV who use methamphetamine"],"prefix":"10.1111","volume":"41","author":[{"given":"Leah","family":"Davis Ewart","sequence":"first","affiliation":[{"name":"Department of Public Health Sciences University of Miami Miller School of Medicine  Miami 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