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We examined factors associated with illicit drug use in the past 6 months and lifetime experiences of self\u2010reported concern with drug use among LGBTQA youth in Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional survey was conducted involving 6418 LGBTQA participants aged 14\u201321\u2009years, 5914 of whom provided information relating to their use of illicit drugs. Multivariable logistic regressions examined demographic factors and life experiences associated with drug use in the past 6 months and lifetime experiences of self\u2010reported concern with drug use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 26.4% of participants aged 14\u201317 and 41.9% aged 18\u201321 reported any drug use in the past 6 months, of whom 23.5% had ever been concerned about their drug use. Cannabis use was most commonly reported (28.3%), followed by ecstasy\/MDMA (7.1%), antidepressants (5.6%) and LSD (3.5%). Higher odds of drug use were reported among cisgender men and those who had experienced homelessness or sexual harassment in the past 12\u2009months. Higher odds of self\u2010identified concern about drug use were observed among participants reporting challenging life experiences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>Rates of illicit drug use among LGBTQA young people in this study were considerably higher than those observed in general population youth studies in Australia and were further elevated among those who had experienced LGBTQA\u2010related prejudice or harassment, or homelessness.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.13585","type":"journal-article","created":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T17:00:22Z","timestamp":1670259622000},"page":"714-728","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Illicit drug use among lesbian, gay, bisexual, pansexual, trans and gender diverse, queer and asexual young people in Australia: Intersections and associated 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