{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:49:29Z","timestamp":1789757369883,"version":"4.0.1"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T00:00:00Z","timestamp":1696464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1140298"],"award-info":[{"award-number":["1140298"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1194483"],"award-info":[{"award-number":["1194483"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1196892"],"award-info":[{"award-number":["1196892"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["2002193"],"award-info":[{"award-number":["2002193"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["2016909"],"award-info":[{"award-number":["2016909"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Prescription drug monitoring programs (PDMP) are increasingly used to identify people prescribed high\u2010dose opioids. However, little is known about whether PDMPs impact opioid agonist treatment (OAT) uptake, the gold standard for opioid use disorder. This study examined the impact of PDMP implementation on OAT initiation among people prescribed opioids, in Victoria, Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>De\u2010identified electronic records from all 464 Victorian general practices included in the POLAR database were used. OAT initiation was defined as a new OAT prescription between 1 April 2017 and 31 December 2020, with no OAT prescriptions in the year prior. Interrupted time series analyses were used to compare outcomes before (April 2017 to March 2019) and after (April 2019 to December 2020) PDMP implementation. Binary logistic regression was used to examine differences in patients' characteristics associated with OAT initiation prior to and after PDMP implementation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 1610 people initiated OAT, 946 before and 664 after PDMP implementation. No significant immediate (step) or longer\u2010term (slope) changes in the rates of OAT initiation were identified following PDMP implementation, after adjusting for seasonality. A high opioid dose (&gt;100\u2009mg oral morphine equivalent) in the 6\u2010months prior to OAT initiation was the only significant characteristic associated with reduced odds of OAT initiation post\u2010PDMP implementation (odds ratio 0.29; 0.23\u20130.37).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>PDMP implementation did not have a significant impact on OAT initiation among people prescribed opioids. Findings suggest additional clinical initiatives that support OAT initiation are required to ensure PDMPs meet their intended target of reducing opioid\u2010related harms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.13754","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T17:37:26Z","timestamp":1696613846000},"page":"1639-1646","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Changes in opioid agonist treatment initiation among people prescribed opioids for pain following voluntary and mandatory prescription drug monitoring program implementation: A time series analysis"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7593-3209","authenticated-orcid":false,"given":"Louisa","family":"Picco","sequence":"first","affiliation":[{"name":"Monash Addiction Research Centre, Eastern Health Clinical School Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Xia","sequence":"additional","affiliation":[{"name":"Monash Addiction Research Centre, Eastern Health Clinical School Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Simon","family":"Bell","sequence":"additional","affiliation":[{"name":"Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences Monash University  Melbourne Australia"},{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Pearce","sequence":"additional","affiliation":[{"name":"Outcome Health  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachelle","family":"Buchbinder","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan I.","family":"Lubman","sequence":"additional","affiliation":[{"name":"Monash Addiction Research Centre, Eastern Health Clinical School Monash University  Melbourne Australia"},{"name":"Turning Point, Eastern Health Clinical School Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5341-1055","authenticated-orcid":false,"given":"Suzanne","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Monash Addiction Research Centre, Eastern Health Clinical School Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32229-9"},{"key":"e_1_2_9_3_1","volume-title":"Prescription opioid overdose deaths","author":"Centers for Disease Control and Prevention","year":"2021"},{"key":"e_1_2_9_4_1","volume-title":"Alcohol, tobacco & other drugs in Australia","author":"Australian Institute of Health and Welfare (AIHW)","year":"2021"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.13795"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000000625"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14-2559"},{"key":"e_1_2_9_8_1","article-title":"Opioid agonist treatment for people who are dependent on pharmaceutical opioids","volume":"9","author":"Nielsen S","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.52002"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j1550"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/dar.12976"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.202000312"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.51095"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2021.109090"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxaa002"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-017-2354-5"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0000000000000608"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2022.103856"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.7326\/M17-3074"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2019.04.007"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2023.104053"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/dar.13652"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2022.07.041"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjhci-2019-100009"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-067746"},{"key":"e_1_2_9_26_1","volume-title":"Census of Population and Housing: Socio\u2010Economic Indexes for Areas (SEIFA), Australia, 2016","author":"Australian Bureau of Statistics","year":"2016"},{"key":"e_1_2_9_27_1","volume-title":"Remoteness Areas","author":"Australian Bureau of Statistics","year":"2023"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.3945"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/coep.12586"},{"key":"e_1_2_9_30_1","unstructured":"Australian Institute of Health and Welfare (AIHW).National Opioid Pharmacotherapy Statistics Annual Data Collection (NOPSAD) 2023. 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