{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T16:30:35Z","timestamp":1784565035777,"version":"3.55.0"},"reference-count":64,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T00:00:00Z","timestamp":1718582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Opioid agonist treatment (OAT) is an effective treatment for opioid dependence syndrome in adults. However, studies on effectiveness of OAT in adolescents are limited; existing studies show varying retention rates. The present study aimed to assess OAT retention rates in adolescent patients with opioid dependence syndrome registered in a community drug treatment clinic in Delhi, India, and to analyse factors associated with retention at 1\u2009year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective cohort study. All adolescents (<jats:italic>n<\/jats:italic>\u2009=\u2009130) aged 10\u201319\u2009years, started on OAT from January 2020 to July 2022 were included. Baseline and follow\u2010up data was extracted from online record system maintained at the clinic. OAT retention rates at different timepoints were assessed. Multivariable logistic regression was used to discern factors associated with one\u2010year retention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The participants' mean age was 16.9 (SD 1.4) years. Mean age of starting opioids was 14.9 (SD 2.2) years; 29.5% (<jats:italic>n<\/jats:italic>\u2009=\u200938) injected opioids. The 6\u2010, 12\u2010, 18\u2010 and 24\u2010month retention rate on OAT was 64.4%, 45.6%, 38.7% and 29% respectively. The retention rates with buprenorphine and methadone were comparable. Multivariate logistic regression showed retention for less than 12\u2009months to be significantly associated with younger age of starting heroin, involvement in illegal activities, absenteeism from school and substance use in family.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>The 12\u2010month retention rates on OAT in adolescents is comparable to retention rates in adults. Various factors associated with early age of onset of opioid use are also associated with lower retention rates on OAT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.13890","type":"journal-article","created":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T12:03:12Z","timestamp":1718625792000},"page":"1835-1844","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of treatment retention rates and predictors of retention on opioid agonist treatment among adolescents"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9413-6846","authenticated-orcid":false,"given":"Pooja","family":"Shakya","sequence":"first","affiliation":[{"name":"Department of Psychiatry Institute of Human Behaviour and Allied Science  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaswant","family":"Jangra","sequence":"additional","affiliation":[{"name":"National Drug Dependence Treatment Centre All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1765-1462","authenticated-orcid":false,"given":"Ravindra","family":"Rao","sequence":"additional","affiliation":[{"name":"National Drug Dependence Treatment Centre All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8872-1886","authenticated-orcid":false,"given":"Ashwani Kumar","family":"Mishra","sequence":"additional","affiliation":[{"name":"National Drug Dependence Treatment Centre All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshan","family":"Bhad","sequence":"additional","affiliation":[{"name":"National Drug Dependence Treatment Centre All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,17]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"World Health Organization.Adolescent health [Internet]. 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