{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T05:23:08Z","timestamp":1787462588757,"version":"build-2736575974"},"reference-count":46,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003107","name":"Bundesministerium f\u00fcr Gesundheit","doi-asserted-by":"publisher","award":["ZMI5\u20102522DSM210"],"award-info":[{"award-number":["ZMI5\u20102522DSM210"]}],"id":[{"id":"10.13039\/501100003107","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We aimed to assess: (i) trends in alcohol\u2010specific \u2014 that is, fully attributable \u2014 morbidity and mortality in the German adult population aged 15\u201369 between 2000 and 2021; and (ii) changes in alcohol\u2010attributable disease burden \u2014 that is, fully and partially alcohol\u2010attributable categories \u2014 for 2006, 2012, 2018 and 2021.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Morbidity data was pulled from hospitalisation and rehabilitation statistics and mortality data was pulled from the causes of death registry. Alcohol use, adjusted for unrecorded consumption, was estimated using the Epidemiological Survey of Substance Abuse and triangulated with per capita consumption from annual sales data. For major disease categories, alcohol\u2010attributable fractions were estimated for males and females by age groups (15\u201329, 30\u201349, 50\u201369\u2009years) using the comparative risk assessment methodology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For males and females, the age\u2010standardised rate of alcohol\u2010specific morbidity peaked in 2012 and decreased thereafter showing a steep decline from 2019 to 2021. The rates of alcohol\u2010specific mortality decreased constantly from 2000 to 2019 but increased from 2019 to 2021. Compared to 2006 the age\u2010standardised alcohol\u2010attributable morbidity and mortality rates in males and females were lower in 2021. For both sexes, the age\u2010standardised alcohol\u2010attributable morbidity and mortality rates and the proportions of morbidity\/mortality rates relative to all\u2010cause morbidity\/mortality decreased between 2006 and 2021.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The declines in alcohol\u2010attributable morbidity and mortality are in line with decreases in consumption and signal that the importance of alcohol in health service utilisation and mortality has weakened. Sex ratios in morbidity and mortality do not indicate a strong converging trend.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.13928","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T05:45:00Z","timestamp":1724910300000},"page":"1662-1675","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Trends in alcohol\u2010attributable morbidity and mortality in Germany from 2000 to 2021: A modelling study"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7282-0217","authenticated-orcid":false,"given":"Ludwig","family":"Kraus","sequence":"first","affiliation":[{"name":"IFT Institut f\u00fcr Therapieforschung, Centre for Mental Health and Addiction Research  Munich Germany"},{"name":"Department of Public Health Sciences, Centre for Social Research on Alcohol and Drugs Stockholm University  Stockholm Sweden"},{"name":"Centre of Interdisciplinary Addiction Research, Department of Psychiatry and Psychotherapy University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"},{"name":"Institute of Psychology, ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"M\u00f6ckl","sequence":"additional","affiliation":[{"name":"IFT Institut f\u00fcr Therapieforschung, Centre for Mental Health and Addiction Research  Munich Germany"},{"name":"Department of Psychiatry and Psychotherapy, University Hospital Ludwig\u2010Maximilians\u2010University Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1231-3760","authenticated-orcid":false,"given":"Jakob","family":"Manthey","sequence":"additional","affiliation":[{"name":"Centre of Interdisciplinary Addiction Research, Department of Psychiatry and Psychotherapy University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"},{"name":"Department of Psychiatry, Medical Faculty University of Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pol","family":"Rovira","sequence":"additional","affiliation":[{"name":"Program on Substance Abuse &amp; WHO Collaborating Centre Public Health Agency of Catalonia  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Olderbak","sequence":"additional","affiliation":[{"name":"IFT Institut f\u00fcr Therapieforschung, Centre for Mental Health and Addiction Research  Munich Germany"},{"name":"Department of Psychiatry and Psychotherapy, University Hospital Ludwig\u2010Maximilians\u2010University Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5665-0385","authenticated-orcid":false,"given":"J\u00fcrgen","family":"Rehm","sequence":"additional","affiliation":[{"name":"Centre of Interdisciplinary Addiction Research, Department of Psychiatry and Psychotherapy University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"},{"name":"Program on Substance Abuse &amp; WHO Collaborating Centre Public Health Agency of Catalonia  Barcelona Spain"},{"name":"Centre for Addiction and Mental Health Institute for Mental Health Policy Research &amp; Campbell Family Mental Health Research Institute  Toronto Canada"},{"name":"Institute of Clinical Psychology and Psychotherapy &amp; Center for Clinical Epidemiology and Longitudinal Studies Technische Universit\u00e4t  Dresden Germany"},{"name":"Department of Psychiatry, Institute of Medical Science, &amp; Dalla Lana School of Public Health University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,28]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"World Health Organization.Global status report on alcohol and health 2018.2018[13 September 2022]. 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