{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:29:59Z","timestamp":1790814599479,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T00:00:00Z","timestamp":1737244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Issues<\/jats:title><jats:p>Alcohol consumption can cause physical, psychological and social problems that can result in hospitalisations. Screening in hospitals helps to determine which patients should be given interventions. In this review, we aimed to summarise the diagnostic test accuracy (DTA) of screening instruments for problematic alcohol use among adults in hospitals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Approach<\/jats:title><jats:p>We searched three databases for studies that assessed validated screening instruments for problematic alcohol use among hospitalised adults. We used the Quality Assessment of Diagnostic Accuracy Studies 2 tool to evaluate the risk of bias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Findings<\/jats:title><jats:p>We included 20 studies in the review. In 11 studies performed in the emergency departments, 5 instruments had a high DTA: the AUDIT, the AUDIT\u2010C, the RAPS4\u2010QF, the 2\u2010question screener and HOLD 5. In the eight studies with inpatients, three instruments had a high DTA: the AUDIT, CAGE\u2010C and CAGE +10 items. Finally, only one of the included studies evaluated outpatients; the authors reported a high DTA for the AUDIT\u2010C.<\/jats:p><\/jats:sec><jats:sec><jats:title>Implication and Conclusions<\/jats:title><jats:p>The results indicate that the AUDIT is an appropriate screening instrument for both inpatients and patients in the emergency department. Moreover, for patients in the emergency department, the AUDIT\u2010C and the RAPS4\u2010QF can be used. More research is needed on outpatients, and several screening instruments have only been validated with one study (i.e., the 2\u2010question screener, DSM\u2010IV\u20102, HOLD 5, CAGE\u2010C and CAGE +10 questions).<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.13987","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T02:25:46Z","timestamp":1737339946000},"page":"505-531","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Screening instruments to detect problematic alcohol use among adults in hospitals and their diagnostic test accuracy: A systematic review"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7586-7176","authenticated-orcid":false,"given":"Jacqueline M.","family":"Bisschop","sequence":"first","affiliation":[{"name":"Jeroen Bosch Hospital  s\u2010Hertogenbosch the Netherlands"},{"name":"Department Tranzo Tilburg School of Social and Behavioural Sciences  Tilburg the Netherlands"},{"name":"Epidemiology and Data Science Amsterdam University Medical Center, University of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik J. 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