{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T23:34:55Z","timestamp":1789256095736,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T00:00:00Z","timestamp":1738540800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009287","name":"NSW Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009287","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>A trial of long\u2010acting injectable buprenorphine (LAIB) in Australian prisons allowed examination of treatment satisfaction and patient\u2010reported outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>UNLOC\u2010T was a 16\u2010week non\u2010randomised open\u2010label study. Men and women aged \u226518\u2009years with moderate\/severe DSM\u20105 opioid use disorder currently serving a custodial sentence \u22656\u2009months were recruited. Participants not in opioid agonist treatment (OAT) commenced LAIB (<jats:italic>n<\/jats:italic>\u2009=\u200967); those already stable on oral methadone treatment were recruited to a comparison arm (<jats:italic>n<\/jats:italic>\u2009=\u200962). The Treatment Satisfaction Questionnaire for Medication (TSQM), Patient Satisfaction Visual Analogue Scale (PS\u2010VAS) and Treatment Burden Questionnaire assessed treatment satisfaction; the Kessler Psychological Distress Scale (K10), 12\u2010Item Short Form Health Survey (SF\u201012) and the Australian Treatment Outcomes Profile (ATOP) measured mental health, physical health and quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among participants receiving LAIB, TSQM global satisfaction scores significantly increased from 68.2 (SD 16.6) to 77.0 (SD 18.4) by week 16 (<jats:italic>p<\/jats:italic>\u2009=\u20090.0041), as did satisfaction measured by the PS\u2010VAS (62.5 [SD 29.2] vs. 79.4 [SD 25.5], <jats:italic>p<\/jats:italic>\u2009=\u20090.0005). Statistically significant improvements between baseline and week 16 were also observed for K10, SF\u201012 (total) and SF\u201012 (mental health) scores. By the end of the study, \u2018successful\u2019 treatment outcomes were observed in the ATOP domains of psychological health (84%), physical health (80%) and quality of life (86%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>Participants inducted and stabilised on LAIB reported high treatment satisfaction and improved health and wellbeing. Results suggest LAIB is acceptable to people with opioid use disorder in custody, supporting scaleup of this medication to increase coverage of OAT in these settings.<\/jats:p><jats:p>Trial registration: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.anzctr.org.au\/\">https:\/\/www.anzctr.org.au<\/jats:ext-link> ACTRN12618000942257.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.14005","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T04:59:17Z","timestamp":1738645157000},"page":"640-648","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Treatment satisfaction and patient reported outcomes among people with opioid use disorder participating in an open\u2010label, non\u2010randomised trial of long\u2010acting injectable buprenorphine treatment in Australian custodial settings"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2049-2669","authenticated-orcid":false,"given":"Bethany","family":"White","sequence":"first","affiliation":[{"name":"Edith Collins Centre for Translational Research in Alcohol, Drugs and Toxicology, Sydney Local Health District  Sydney Australia"},{"name":"Specialty of Addiction Medicine, Faculty of Medicine and Health, The University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7164-2623","authenticated-orcid":false,"given":"Sophia","family":"Little","sequence":"additional","affiliation":[{"name":"Edith Collins Centre for Translational Research in Alcohol, Drugs and Toxicology, Sydney Local Health District  Sydney Australia"},{"name":"Specialty of Addiction Medicine, Faculty of Medicine and Health, The University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul S.","family":"Haber","sequence":"additional","affiliation":[{"name":"Edith Collins Centre for Translational Research in Alcohol, Drugs and Toxicology, Sydney Local Health District  Sydney Australia"},{"name":"Specialty of Addiction Medicine, Faculty of Medicine and Health, The University of Sydney  Sydney Australia"},{"name":"Drug &amp; Alcohol Clinical Research &amp; Improvement Network  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jillian","family":"Roberts","sequence":"additional","affiliation":[{"name":"Drug &amp; Alcohol Clinical Research &amp; Improvement Network  Sydney Australia"},{"name":"Justice Health and Forensic Mental Health Network  Sydney Australia"},{"name":"Drug &amp; Alcohol Clinical Services, Hunter New England Local Health District  Newcastle Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Nolan","sequence":"additional","affiliation":[{"name":"Hunter Medical Research Institute  Newcastle Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5229-8257","authenticated-orcid":false,"given":"Nicholas","family":"Lintzeris","sequence":"additional","affiliation":[{"name":"Specialty of Addiction Medicine, Faculty of Medicine and Health, The University of Sydney  Sydney Australia"},{"name":"Drug &amp; Alcohol Clinical Research &amp; Improvement Network  Sydney Australia"},{"name":"Drug and Alcohol Services, South Eastern Sydney Local Health District  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2394-5966","authenticated-orcid":false,"given":"Adrian J.","family":"Dunlop","sequence":"additional","affiliation":[{"name":"Drug &amp; Alcohol Clinical Research &amp; Improvement Network  Sydney Australia"},{"name":"Drug &amp; Alcohol Clinical Services, Hunter New England Local Health District  Newcastle Australia"},{"name":"Faculty of Health and Medicine, University of Newcastle  Newcastle Australia"},{"name":"Healthcare Transformation Research Program, Hunter Medical Research Institute  Newcastle Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32229-9"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI134708"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.102311"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.14636"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.1052"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.13877"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2010.02990.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxy002"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30466-4"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2018.12.003"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/00952990.2024.2360984"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.9041"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/dar.13616"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/SAR.S266838"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2019.11.004"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2021.108959"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13722-022-00288-4"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.15627"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-2-12"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-019-00168-5"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-12-109"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291702006074"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/dar.13346"},{"key":"e_1_2_9_26_1","unstructured":"LintzerisN DeaconR MillsL BrunoR BlackE HolmesJ et al.The Australian Treatment Outcomes Profile (ATOP) manual 2: research and service evaluation. Available from:www.seslhd.health.nsw.gov.au\/australian\u2010treatment\u2010outcomes\u2010profile. Retrieved 25 July 2023"},{"key":"e_1_2_9_27_1","volume-title":"Some heteroskedasticity consistent covariance matrix estimators with improved finite sample properties","author":"MacKinnon JG","year":"1983"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2022.103788"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.9708"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2019.09.004"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-022-12685-0"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-022-08687-8"},{"key":"e_1_2_9_33_1","volume-title":"The health of Australia's prisoners 2018","author":"Australian Institute of Health and Welfare","year":"2019"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2023.103978"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2023.104255"},{"key":"e_1_2_9_36_1","volume-title":"National opioid pharmacotherapy statistics annual data collection","author":"Australian Institute of Health and Welfare","year":"2024"}],"container-title":["Drug and Alcohol Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dar.14005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T04:27:34Z","timestamp":1739334454000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dar.14005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/dar.14005"],"URL":"https:\/\/doi.org\/10.1111\/dar.14005","archive":["Portico"],"relation":{},"ISSN":["0959-5236","1465-3362"],"issn-type":[{"value":"0959-5236","type":"print"},{"value":"1465-3362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-07-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}