{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T16:41:38Z","timestamp":1785170498653,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T00:00:00Z","timestamp":1742860800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009553","name":"Agentura pro zdravotnick\u00fd v\u00fdzkum \u010cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["NU22\u2010D\u2010146"],"award-info":[{"award-number":["NU22\u2010D\u2010146"]}],"id":[{"id":"10.13039\/501100009553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The aim was to analyse mortality and estimate the life expectancy among people hospitalised for alcohol use disorders (AUD) compared with the general Czech population aged \u226520\u2009years. A temporal perspective on excess mortality was used, covering three recent calendar periods before and during the pandemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three retrospective cohorts of the target population were constructed using registry\u2010based data. The target population was defined as all adult patients (aged \u226520\u2009years) admitted to the hospital for AUD (ICD\u201010 dg. of F10.x) between 2010 and 2021. Age\u2010adjusted mortality rates and life expectancies were calculated for the comparative analysis. Official Czech mortality and vital statistics were used for the comparison. A Poisson log\u2010linear regression model was used to test the effect of the pandemic period (2020\u20132021) on mortality in the AUD target population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At age 20, the estimated life expectancy of the AUD target was 21\u201327\u2009years less than that of the Czech general population. Excess mortality was relatively highest in young people aged 20\u201334\u2009years and in adults aged 35\u201349\u2009years. During the pandemic period 2020\u20132021, mortality rates in the target AUD increased significantly. However, relative inequalities with the general Czech population did not change significantly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusions<\/jats:title><jats:p>People hospitalised for AUD have much higher mortality rates, resulting in markedly reduced life expectancy. During the pandemic, their mortality rates increased even more. However, the increase was no greater than in the general Czech population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dar.14045","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T13:48:46Z","timestamp":1743169726000},"page":"1229-1239","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Excess mortality in people hospitalised for alcohol use disorders before and during the pandemic \u2013 A registry\u2010based retrospective cohort study"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9369-7721","authenticated-orcid":false,"given":"Ladislav","family":"K\u00e1\u017em\u00e9r","sequence":"first","affiliation":[{"name":"National Institute of Mental Health  Klecany Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4989-4504","authenticated-orcid":false,"given":"Ond\u0159ej","family":"\u0160\u00edba","sequence":"additional","affiliation":[{"name":"National Institute of Mental Health  Klecany Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4488-4787","authenticated-orcid":false,"given":"Barbora","family":"Orl\u00edkov\u00e1","sequence":"additional","affiliation":[{"name":"National Institute of Mental Health  Klecany Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31775-1"},{"key":"e_1_2_12_3_1","first-page":"174","article-title":"Alcohol and mortality: global alcohol\u2010attributable deaths from cancer, liver cirrhosis, and injury in 2010","volume":"35","author":"Rehm J","year":"2013","journal-title":"Alcohol Res"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.21101\/cejph.a5728"},{"key":"e_1_2_12_5_1","volume-title":"N\u00e1rodn\u00ed v\u00fdzkum u\u017e\u00edv\u00e1n\u00ed tab\u00e1ku a alkoholu v \u010cesk\u00e9 republice 2021, NAUTA [National Survey on Tobacco and Alcohol Use in the Czech Republic 2021, NAUTA]","author":"Cs\u00e9my L","year":"2022"},{"key":"e_1_2_12_6_1","first-page":"84","article-title":"Struktura mortality osob \u00fastavn\u011b l\u00e9\u010den\u00fdch pro poruchy vyvolan\u00e9 alkoholem v \u010cR v letech 1994\u20132013 [Structure of mortality of persons hospitalised for alcohol use disorders in the Czech Republic from 1994 to 2013]","volume":"17","author":"Nechansk\u00e1 B","year":"2017","journal-title":"Adiktologie"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(22)00335-2"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2021.109150"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/dar.13074"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2020.05.035"},{"key":"e_1_2_12_11_1","volume-title":"Psychiatrick\u00e1 ro\u010denka 2021 [Psychiatric Yearbook 2021]","author":"Institute of Health Information and Statistics","year":"2022"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/dar.13573"},{"key":"e_1_2_12_13_1","volume-title":"Alcohol\u2010specific deaths in the UK: registered in 2021","author":"Office for National Statistics","year":"2022"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.4308"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcohol.2020.10.003"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2022.07.007"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmedr.2022.101751"},{"key":"e_1_2_12_18_1","volume-title":"Revision of the European standard population: report of the Eurostat's task force","author":"Eurostat","year":"2013"},{"key":"e_1_2_12_19_1","volume-title":"Statistical methods in cancer research. 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