{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:39:42Z","timestamp":1791877182427,"version":"4.3.4"},"reference-count":7,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Medicinal cannabis prescribing in Australia has increased markedly, including for psychiatric indications where evidence of benefit is limited and of low certainty. The rise of highly commercialised prescribing models has raised concerns regarding patient safety, particularly for those with pre\u2010existing psychiatric or addiction vulnerabilities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>This case series describes three young men (aged 20\u201324) with psychiatric disorders and substance use vulnerabilities who were prescribed medicinal cannabis. The cases illustrate potential iatrogenic harms, including cannabinoid hyperemesis syndrome, cannabis use disorder, paranoia, affective instability and the delaying of other treatment. In two cases, prescribing continued despite emerging adverse outcomes or a formal request for cessation of prescribing from an addiction specialist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion and Conclusion<\/jats:title>\n                    <jats:p>These cases highlight the potential iatrogenic harms associated with the current medicinal cannabis prescribing practices in Australia, especially among those with psychiatric and substance use vulnerabilities. More rigorous, evidence\u2010aligned prescribing, clearer exclusion criteria and a lower threshold for discontinuation when harms emerge are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dar.70255","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T05:13:18Z","timestamp":1788239598000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Potential Iatrogenic Harms From Medicinal Cannabis Prescribing in Australia: A Case Series"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2111-0932","authenticated-orcid":false,"given":"Richard","family":"Bradlow","sequence":"first","affiliation":[{"name":"Department of Psychiatry Monash University  Melbourne Australia"},{"name":"The Victoria Clinic  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0413-5769","authenticated-orcid":false,"given":"James","family":"Sorensen","sequence":"additional","affiliation":[{"name":"The Victoria Clinic  Melbourne Australia"},{"name":"Department of Psychiatry Alfred Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Cunningham","sequence":"additional","affiliation":[{"name":"The Victoria Clinic  Melbourne Australia"},{"name":"Department of Psychiatry Alfred Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Daugherty","sequence":"additional","affiliation":[{"name":"The Victoria Clinic  Melbourne Australia"},{"name":"Department of Psychiatry St Vincent's Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1144-5600","authenticated-orcid":false,"given":"Eric","family":"Hadinata","sequence":"additional","affiliation":[{"name":"The Victoria Clinic  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferghal","family":"Armstrong","sequence":"additional","affiliation":[{"name":"The Victoria Clinic  Melbourne Australia"},{"name":"Department of Addiction Eastern Health  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6049-9654","authenticated-orcid":false,"given":"Nazila","family":"Jamshidi","sequence":"additional","affiliation":[{"name":"The Victoria Clinic  Melbourne Australia"},{"name":"Department of Addiction Royal Melbourne Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2024.111263"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.52586"},{"key":"e_1_2_8_4_1","volume-title":"Doctors Warn of Significant Increase in People Hospitalised With Psychosis After Being Prescribed Medicinal Cannabis","author":"Miles J.","year":"2024"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(26)00015-5"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1142680"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.52313"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/crps\/8870476"}],"container-title":["Drug and Alcohol Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dar.70255","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dar.70255","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dar.70255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:30:25Z","timestamp":1790307025000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dar.70255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/dar.70255"],"URL":"https:\/\/doi.org\/10.1111\/dar.70255","archive":["Portico"],"relation":{},"ISSN":["0959-5236","1465-3362"],"issn-type":[{"value":"0959-5236","type":"print"},{"value":"1465-3362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]},"assertion":[{"value":"2026-04-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70255"}}