{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T06:41:51Z","timestamp":1776148911943,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T00:00:00Z","timestamp":1365465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acne inversa (AI) is a common chronic inflammatory disease that has a profound impact on the patients\u00ed quality of life. We hypothesized a higher level of depression in AI patients compared to controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We studied depression in patients with AI and control subjects. Additionally, we evaluated whether the severity of the disease, anxiety, sexual distress and acute inflammation may have an influence on depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>The Hospital Anxiety and Depression Scale (HADS) was given to 90 voluntary study participants to assess depression in AI patients and in age\u2010, gender\u2010, and BMI\u2010matched controls. Moreover, the correlation between depression and conjectural influencing factors was evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study demonstrated that AI patients have a higher depression score than matched controls. Importantly, 38.6% of AI patients are affected by depression compared to 2.4% of the control subjects. In contrast to the duration of the disease and the AI patients\u00ed age, anxiety and sexual distress showed a strong correlation with the degree of depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients with AI have a higher risk of developing depression. Physicians should be alert to the possible development of depression when treating patients with this disorder.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ddg.12067","type":"journal-article","created":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T05:52:35Z","timestamp":1365486755000},"page":"743-749","source":"Crossref","is-referenced-by-count":26,"title":["Depression is a frequent co\u2010morbidity in patients with acne inversa"],"prefix":"10.1111","volume":"11","author":[{"given":"Agata","family":"Kurek","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Hospital Charit\u00c8  Berlin Germany"},{"name":"Interdisciplinary Group of Molecular Immunopathology Dermatology\/Medical Immunology, University Hospital Charit\u00c8  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva Milena","family":"Johanne Peters","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Hospital Charit\u00c8  Berlin Germany"},{"name":"Psychoneuroimmunology, Departments of Psychosomatics and Psychotherapy Justus\u2010Liebig University  Gieflen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Sabat","sequence":"additional","affiliation":[{"name":"Interdisciplinary Group of Molecular Immunopathology Dermatology\/Medical Immunology, University Hospital Charit\u00c8  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfram","family":"Sterry","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Hospital Charit\u00c8  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylke","family":"Schneider\u2010Burrus","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Hospital Charit\u00c8  Berlin 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