{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:37:52Z","timestamp":1790318272533,"version":"4.1.0"},"reference-count":67,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T00:00:00Z","timestamp":1401321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>At the time of diagnosis primary cutaneous lymphomas are limited to the skin. T\u2010cell lymphomas represent at least two thirds of all primary cutaneous lymphomas with mycosis fungoides and S\u00e9zary syndrome being the most frequent entities. A precise staging based on clinical, histological, immunohistological and molecular biological criteria is crucial for selecting the appropriate therapy. Since curative treatment is only possible in exceptional cases, the aim of any therapy is to achieve healing of the skin lesions, minimizing relapses, preventing progression and maintaining the quality of life. While in early disease stages skin\u2010directed therapy is being used, in later stages systemic treatments become more important. This work aims to provide an overview of established and new therapies for the treatment of mycosis fungoides and S\u00e9zary syndrome.<\/jats:p>","DOI":"10.1111\/ddg.12376","type":"journal-article","created":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T13:07:06Z","timestamp":1401368826000},"page":"561-569","source":"Crossref","is-referenced-by-count":13,"title":["New and established treatment options for mycosis fungoides and S\u00e9zary syndrome \u2013 an update"],"prefix":"10.1111","volume":"12","author":[{"given":"Susanne","family":"Dugas\u2010Breit","sequence":"first","affiliation":[{"name":"Department of Dermatology Fachklinik Hornheide  M\u00fcnster"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans\u2010Joachim","family":"Schulze","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fachklinik Hornheide  M\u00fcnster"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Hallermann","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fachklinik Hornheide  M\u00fcnster"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2007.06337.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12015_5"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12237_suppl"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27627"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2007.00971.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2405044"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-11-251926"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09587.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-04-153031"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-6398"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.07.049"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198912283212603"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.3241"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199704103361506"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2002.tb04208.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000236781"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1987.5.11.1796"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.2.165"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/2013.jamadermatol.541"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04433.x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12620"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.3.325"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2002.01363.x"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1159\/000241302"},{"key":"e_1_2_9_27_1","first-page":"199","article-title":"Carmustin\u00a0(Bischloroethyl\u2010 nitrosourea,\u00a0BCNU). In: Szeimies R: Tumoren der Haut: Grundlagen, Diagnostik und Therapie in der Dermatologischen Onkologie","author":"Wozel G","year":"2010","journal-title":"Stuttgart: Georg Thieme Verlag KG"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90241-4"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00614_10.x"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.3.305"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(98)00218-1"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.06.1918"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00553-1"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2012.05.034"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10905.x"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.11.6202"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.03128.x"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.123482"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2008.11.017"},{"key":"e_1_2_9_40_1","first-page":"308","article-title":"Palliative total skin electron beam therapy (TSEBT) for advanced cutaneous T\u2010cell lymphoma","volume":"18","author":"Funk A","year":"2008","journal-title":"Eur J Dermatol"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.12.016"},{"key":"e_1_2_9_42_1","first-page":"487","article-title":"Case experience of 308\u2010nm excimer laser therapy compatibility with PUVA and oral bexarotene for the treatment of cutaneous lesions in mycosis fungoides","volume":"12","author":"Huang J","year":"2013","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1396-0296.2003.01643.x"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-78771-3_30"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/82.3.208"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09475.x"},{"key":"e_1_2_9_47_1","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1684\/ejd.2012.1857","article-title":"Combined oral alitretinoin and narrowband UVB treatment of cutaneous T cell lymphoma: favourable response after multiple ineffective systemic therapies","volume":"22","author":"Motschenbacher S","year":"2012","journal-title":"Eur J Dermatol"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20952"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11156.x"},{"key":"e_1_2_9_50_1","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.1182\/blood.V122.21.4379.4379","article-title":"Response of rare variants of cutaneous T cell lymphoma (CTCL) to treatment with bexarotene. A prospective German DeCOG trial","volume":"122","author":"Weichenthal M","year":"2013","journal-title":"Blood"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.05.038"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12311"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428190903216770"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0609.2003.00143.x"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2007.11.009"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08620.x"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-12-062877"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.52.0924"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.10.2434"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.28.9066"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.21.6150"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2013.02.020"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(03)01591-3"},{"key":"e_1_2_9_64_1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/ddg.12012","article-title":"Treatment of advanced cutaneous T\u2010cell lymphomas with non\u2010pegylated liposomal doxorubicin \u2013 consensus of the lymphoma group of the Working Group Dermatologic Oncology","volume":"11","author":"Assaf C","year":"2013","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.3816\/CLM.2006.n.039"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdp508"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.8301"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1159\/000151510"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fddg.12376","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.12376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:35:39Z","timestamp":1696332939000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.12376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,29]]},"references-count":67,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1111\/ddg.12376"],"URL":"https:\/\/doi.org\/10.1111\/ddg.12376","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,29]]}}}