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In addition to the evidence\u2010 and consensus\u2010based recommendation on the treatment of HE, the guidelines cover mainly consensus\u2010based diagnostic aspects and preventive measures (primary and secondary prevention). Treatment recommendations include non\u2010pharmacological interventions, topical, physical and systemic treatments. Topical corticosteroids are recommended as first line treatment in the management of HE, however continuous long\u2010term treatment beyond six weeks only when necessary and under careful medical supervision. Alitretinoin is recommended as a second line treatment (relative to topical corticosteroids) for patients with severe chronic HE. Randomized control trials (RCT) are missing for other used systemic treatments and comparison of systemic drugs in \u201chead\u2010to\u2010head\u201d RCTs are needed.<\/jats:p><jats:p>The guidelines development group is a working group of the European Society of Contact Dermatitis (ESCD) and has carefully tried to reconcile opposite views, define current optimal practice and provide specific recommendations, and meetings have been chaired by a professional moderator of the AWMF (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften; Association of the Scientific Medical Societies in Germany).<\/jats:p><jats:p>No financial support was given by any medical company. The guidelines are expected to be valid until December 2017 at the latest.<\/jats:p>","DOI":"10.1111\/ddg.12510","type":"journal-article","created":{"date-parts":[[2015,1,6]],"date-time":"2015-01-06T12:30:26Z","timestamp":1420547426000},"page":"77-84","source":"Crossref","is-referenced-by-count":39,"title":["Guidelines for diagnosis, prevention and treatment of hand eczema \u2013 short version"],"prefix":"10.1111","volume":"13","author":[{"given":"Thomas L","family":"Diepgen","sequence":"first","affiliation":[{"name":"Department of Clinical Social Medicine Occupational and Environmental Medicine University Hospital Heidelberg  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus E","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Southern Denmark  Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Chosidow","sequence":"additional","affiliation":[{"name":"APHP 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