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Continuous treatment of onychomycosis with terbinafine represents the most effective systemic therapy. Terbinafine or itraconazole are the safest and most effective antimycotic agents for the treatment of onychomycosis in children. For laser therapy of onychomycosis, only a few studies on clinical efficacy are available. Regarding tinea capitis, targeted species\u2010specific therapy of dermatophytosis of the scalp is currently recommended. Terbinafine, yet also itraconazole and fluconazole, are effective in tinea capitis caused by <jats:italic>Trichophyton<\/jats:italic> species. <jats:italic>Microsporum<\/jats:italic> infections of the scalp are preferably treated with griseofulvin, alternatively with itraconazole or fluconazole. Terbinafine is less effective.<\/jats:p><jats:p>Candidal intertrigo are topically treated with nystatin, but azoles or ciclopirox olamine are also suitable candidates. Systemically, fluconazole or itraconazole are used. Topical and systemic antimycotics are equivalent forms of therapy in acute vulvovaginal mycosis. Fluconazole is the drug of choice in chronic recurrent vulvovaginal mycosis caused by <jats:italic>Candida albicans<\/jats:italic>. Ketoconazole shows very good efficacy in tinea versicolor. With respect to systemic treatment of severe and widespread tinea versicolor, itraconazole is the drug of choice.<\/jats:p>","DOI":"10.1111\/ddg.12689","type":"journal-article","created":{"date-parts":[[2015,4,30]],"date-time":"2015-04-30T10:06:05Z","timestamp":1430388365000},"page":"387-411","source":"Crossref","is-referenced-by-count":19,"title":["Mycology \u2013 an update Part 3: Dermatomycoses: topical and systemic therapy"],"prefix":"10.1111","volume":"13","author":[{"given":"Pietro","family":"Nenoff","sequence":"first","affiliation":[{"name":"Medical Microbiology Laboratory  M\u00f6lbis Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constanze","family":"Kr\u00fcger","sequence":"additional","affiliation":[{"name":"Medical Microbiology Laboratory  M\u00f6lbis Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Paasch","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, Leipzig University Hospital and Leipzig University Faculty of Medicine  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Ginter\u2010Hanselmayer","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, Medical University Graz  Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/1516-3180.20141322T1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/ddg.12374","article-title":"Microorganisms of the toe web and their importance for erysipelas of the leg","volume":"12","author":"M\u00fcller DP","year":"2014","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_6_4_1","first-page":"1135","article-title":"Treatment of interdigital tinea pedis: once\u2010daily therapy with sertaconazole nitrate","volume":"10","author":"Weinberg JM","year":"2011","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01807.x"},{"key":"e_1_2_6_6_1","first-page":"178","article-title":"Antimykotikum plus Glukokortikoid. 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