{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T15:57:44Z","timestamp":1779206264281,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,27]],"date-time":"2016-01-27T00:00:00Z","timestamp":1453852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background and objectives<\/jats:title><jats:p>Pemphigus is a group of autoimmune diseases characterized by intraepidermal acantholytic blisters. Isomorphic responses, or Koebner phenomenon (KP), defined as the appearance of typical lesions of a disease following trauma are rarely reported in pemphigus. Our aim was to present patients who developed new pemphigus lesions as a result of skin trauma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>The medical files of pemphigus patients from the Autoimmune Bullous Diseases Research Center, who had a history of trauma before the onset or flare of their disease, between 1999 and 2013 were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010six pemphigus vulgaris (PV) patients had a history of trauma. Thirteen patients developed new\u2010onset PV and the other 23 had previously been diagnosed with PV. Pemphigus lesions developed most often following major surgeries including abdominal, orthopedic, and chest surgeries as well as dental procedures, blunt physical trauma, and skin surgeries. Moreover, post\u2010cataract laser surgery, burns, radiation therapy, and physiotherapy were also shown to induce pemphigus. Mean time between trauma and lesions was 4.7 weeks for recurrent PV and 15.0 weeks for new\u2010onset PV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Unnecessary surgery and blunt trauma should be avoided in pemphigus patients. Furthermore, posttraumatic pemphigus should be suspected in poorly healing surgical wounds and confirmatory biopsies are mandatory.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ddg.12738","type":"journal-article","created":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T04:10:56Z","timestamp":1453954256000},"page":"166-171","source":"Crossref","is-referenced-by-count":13,"title":["Trauma\u2010induced pemphigus: a case series of 36 patients"],"prefix":"10.1111","volume":"14","author":[{"given":"Maryam","family":"Daneshpazhooh","sequence":"first","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina","family":"Fatehnejad","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziba","family":"Rahbar","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamran","family":"Balighi","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narges","family":"Ghandi","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Ghiasi","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robabeh","family":"Abedini","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vahideh","family":"Lajevardi","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheyda","family":"Chams\u2010Davatchi","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2011.01.016"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000111506"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1994.tb01724.x"},{"issue":"10","key":"e_1_2_6_5_1","first-page":"1319","article-title":"Ionizing radiation\u2010induced pemphigus","volume":"126","author":"Low GJ","year":"1990","journal-title":"Case presentations and literature review. 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