{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T21:18:15Z","timestamp":1770412695647,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,10,29]],"date-time":"2015-10-29T00:00:00Z","timestamp":1446076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The term epidermolysis bullosa (EB) includes a group of rare genodermatoses characterized by mutational impairment of the structural and functional integrity of intraepidermal adhesion and dermoepidermal anchorage. Clinically, these disorders are marked by increased skin fragility as well as characteristic mechanically inducible blisters on the skin and mucous membranes. Extracutaneous manifestations and their complications in other epithelialized organs render EB a multi\u2010system disease associated with significant morbidity and mortality. Cornerstones of a dynamically changing healthcare structure include precise and early diagnosis; coordinated, multidisciplinary, individually adjusted patient care at specialized centers; optimized symptomatic therapies; and access to research\u2010based, potentially curative therapeutic strategies.<\/jats:p>","DOI":"10.1111\/ddg.12774","type":"journal-article","created":{"date-parts":[[2015,10,29]],"date-time":"2015-10-29T16:58:12Z","timestamp":1446137892000},"page":"1125-1133","source":"Crossref","is-referenced-by-count":18,"title":["Hereditary epidermolysis bullosa"],"prefix":"10.1111","volume":"13","author":[{"given":"Martin","family":"Laimer","sequence":"first","affiliation":[{"name":"Department of Dermatology Paracelsus Medical University Salzburg  Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Prodinger","sequence":"additional","affiliation":[{"name":"Department of Dermatology Paracelsus Medical University Salzburg  Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johann W.","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Paracelsus Medical University Salzburg  Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-12"},{"key":"e_1_2_11_3_1","first-page":"24","volume-title":"Life with Epidermolysis Bullosa (EB): Etiology, diagnosis, multidisciplinary care and therapy","author":"Fine JD","year":"2008"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.02.004"},{"key":"e_1_2_11_5_1","first-page":"S90","article-title":"Diverse TGF\u2010beta signalling activation in fibroblasts from phenotypically discordant monozygotic twins with recessive dystrophic epidermolysis bullosa","volume":"132","author":"Di Salvio M","year":"2012","journal-title":"J Invest Dermatol"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2013.17"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202x.2001.01591.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1747.2003.12639.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddv066"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2009.10.024"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.4833"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2005.039685"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2010.086751"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81894-2"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1086\/497344"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2008.02.006"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2009.10.020"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.03.053"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21576"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/320403"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.01.903"},{"key":"e_1_2_11_22_1","volume-title":"Life with Epidermolysis Bullosa (EB): Etiology, diagnosis, multidisciplinary care and therapy","author":"Fine JD","year":"2008"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12604"},{"issue":"2","key":"e_1_2_11_24_1","article-title":"Epidermolysis bullosa: Part II \u2013 Diagnosis and Management","volume":"28","author":"Murrell DF","year":"2010","journal-title":"Dermatol Clin"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-227-8_30"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2010.01.015"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2010.02.004"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.10"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-8-69"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fddg.12774","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fddg.12774","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.12774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T20:11:45Z","timestamp":1696363905000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.12774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,29]]},"references-count":28,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1111\/ddg.12774"],"URL":"https:\/\/doi.org\/10.1111\/ddg.12774","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,29]]}}}