{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T03:40:09Z","timestamp":1718854809575},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,10,21]],"date-time":"2016-10-21T00:00:00Z","timestamp":1477008000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In recent years, cardiac comorbidities in psoriasis patients have increasingly moved into the focus of clinical research. The objective of the present study was to evaluate myocardial scintigraphy as a screening method in patients with psoriasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>Assessment of various comorbidities in 50 psoriasis patients without clinical symptoms of cardiac disease. Myocardial scintigraphy was employed to detect cardiac risk\/exercise\u2010induced ischemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010eight patients (56\u00a0%) had pathological findings on myocardial scintigraphy. Fourteen individuals showed evidence of small\u2010vessel disease (cardiac syndrome\u00a0X). Other comorbidities included obesity, arterial hypertension, nicotine and alcohol abuse, as well as elevated CRP levels. Frequencies largely corresponded to those reported in the recent literature. There was no significant correlation between the severity of psoriasis or any comorbidities and pathological findings on myocardial scintigraphy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Myocardial scintigraphy seems to be a very sensitive, noninvasive method for the early detection of cardiac comorbidities in psoriasis patients. However, determining its true diagnostic value will require larger studies with control subjects and control methods such as coronary angiography.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ddg.12892","type":"journal-article","created":{"date-parts":[[2016,10,21]],"date-time":"2016-10-21T16:38:52Z","timestamp":1477067932000},"page":"1007-1014","source":"Crossref","is-referenced-by-count":0,"title":["Myocardial scintigraphy \u2013 a method for detecting cardiac comorbidity in psoriasis patients?"],"prefix":"10.1111","volume":"14","author":[{"given":"Markus","family":"Zutt","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergology Medical Center Bremen\u2010Mitte Bremen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hagen","family":"Rudolph","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology Medical Center Bremen\u2010Mitte Bremen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kjell Matthias","family":"Kaune","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology Medical Center Bremen\u2010Mitte Bremen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werner","family":"Wosniok","sequence":"additional","affiliation":[{"name":"Institute for Statistics University of Bremen Bremen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"G\u00e4rtner","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Medical Center Bremen\u2010Mitte Bremen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Linke","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Medical Center Bremen\u2010Mitte Bremen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2009.07083_supp.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3413\/Nukmed-0550-12-12"},{"key":"e_1_2_6_4_1","unstructured":"R Core Team.R: A language and environment for statistical computing. 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